Ion Channels as Therapeutic Targets for Multiple Diseases

Novel approaches for screening sodium channel function in drug discovery
Steve Petrou Howard Florey Institute

Translational promise and physiological insights in Aquaporin drug discovery
Andrea Yool University of Adelaide

The capsaicin receptor TRPV1, as a target for chronic pain therapy
Peter McIntyre University of Melbourne

The Purinergic P2X7 channel/pore and Mood Disorders
Jim Wiley University of Sydney

Myopathies and Muscle Regeneration

Using gene transfer technology to study muscle diseases
Paul Gregorevic The Baker Heart Research Institute

Muscle hypertrophy and IGF-1 isoforms: is bigger better?
Thea Shavlakadze University of Western Australia

Novel regeneration in nemaline myopathy
Anthony Kee Children's Medical Research Institute, Westmead

Acute quadriplegic myopathy in ICU patients: Underlying mechanisms and intervention strategies.
Lars Larsson Uppsala University, Sweden

Signals Mediating Exercise-Induced Skeletal Muscle Remodelling

Organiser: Mark Hargreaves

Histone modifications and skeletal muscle metabolic gene expression
Sean McGee University of Melbourne

Molecular regulation of skeletal muscle mass
Aaron Russell Deakin University

Calpains and skeletal muscle function
Robyn Murphy La Trobe University

A novel role for beta-adrenoceptor signalling in the regulation of skeletal muscle mass
James Ryall NIAMS/National Institutes of Health

Role of ROS in Cardiovascular Function and Disease

NADPH oxidase: role in muscular dystrophy
Nick Whitehead University of Sydney

ROS functions in the endothelium
Grant Drummond Monash University

Cross talk between the L-type calcium channel and the mitochondria
Livia Hool The University of Western Australia

Reactive oxygen species (ROS) and insulin resistant hypertrophic cardiomyopathy
Lea Delbridge University of Melbourne

Cardiac Growth and Ageing

Organisers: Lea Delbridge and John Headrick

Cardiac Excitation-Contraction Coupling and Ageing
Susan Howlett Dalhousie University, Canada

Cardioprotective signalling in aged ischemic hearts
John Headrick Griffith University

Phosphoinositide 3-kinase (PI3K, p110α) and adaptive growth in the heart
Julie McMullen Baker Institute

Metabolic challenges for cardiac mitochondria:from womb to tomb
Salvatore Pepe Murdoch Children's Research Institute

Epithelial Cell Biology

Organisers: Stefan Bröer and Phil Poronnik

Diabetes and ACE2; light on the dark side of the renin angiotensin system
Merlin Thomas Baker Institute

A GFP-based complementation screen for protein:protein interactions for the angiotensin type 1 receptor
Walter Thomas University of Queensland

Extracellular pH shifts and their consequences for secretory epithelial cells
Peter Thorn University of Queensland

Purinergic regulation of epithelial Na⁺ channels
Anuwat Dinudom University of Sydney

An insight into epithelial cells through rare disorders
Stefan Bröer Australian National University

Insights into renal albumin handling
Phil Poronnik University of Queensland

Skeletal Muscle: an Endocrine Organ

Organiser: Mark Febbraio

PGC-1α in muscle links metabolism to inflammation
Christoph Handschin University of Zurich, Switzerland

Role of protease-activated receptors (PARs) in muscle inflammation and cytokine release
Anthony Bakker University of Western Australia

Myokines and metabolic regulation
Mark Febbraio Baker Institute

Signaling in Cell Secretion

Organiser: Chen Chen and Peter Thorn

Complex interactions between ghrelin and obestatin in the regulation of GH secretion and food intake: does obestatin really exist?
Jacques Epelbaum University of Paris

Integrating studies of proteins and lipids: dissecting the mechanism of Ca²⁺-triggered membrane fusion
Jens Coorssen University of Western Sydney

The behaviour and control of post exocytic vesicles
Peter Thorn University of Queensland

Receptor- and metabolite-mediated increase in [Ca²⁺]_i in pancreatic islet cells by free fatty acids
Chen Chen University of Queensland

Signaling in Smooth Muscles

Organisers: James Brock and Dirk van Helden

Ca²⁺ phase waves - a fundamental mechanism underlying propagation of gastric slow waves
Dirk van Helden University of Newcastle

Spontaneous electrical and Ca²⁺ signals underlying the autorhythmicity that drives pyeloureteric peristalsis
Richard Lang Monash University

Molecular and biophysical properties of smooth muscle-type voltage-gated Na⁺ channels
Noriyoshi Teramoto Kyushu University, Japan

Do K⁺ channels play a role in noradrenergic signalling in vascular smooth muscle?
James Brock Prince of Wales Medical Research Institute

Regulation of Trafficking of Membrane Transporters by Intracellular Signaling Systems

Organiser: Anuwat Dinudom

Regulation of receptors and transporters by the Nedd4 family of ubiquitin ligases
Sharad Kumar Institute of Medical and Veterinary Science, South Australia

New insights into the formation and function of caveolae
Rob Parton University of Queensland

The physiological roles of sulfate transporters
Daniel Markovich University of Queensland

The role of phospholipids in controlling GLUT4 exocytosis
Will Hughes Garvan Institute