9:00

1105

T.R. Moopanar, X-H. Xiao, D.G. Allen

AICAR, an AMP kinase activator, inhibits the activity of the Na⁺/H⁺ exchanger in rat ventricular myocytes

9:15

1106

William A. Macdonald, D. George Stephenson

Effect of ADP on twitch force in mechanically skinned fibres of the rat

9:30

1107

X-H. Xiao, D.G. Allen

The cardioprotective effects of Na⁺-H⁺ exchanger inhibition and K_ATP channel activation are additive

9:45

1108

Felice Beitzel, Paul Gregorevic, James G. Ryall, David R. Plant, Gordon S. Lynch

Fenoterol treatment enhances functional repair of skeletal muscle following myotoxic injury

10:00

1109

Damian G. Anderson, Andrew D. Williams, Michael F. Carey, Alan Hayes

Mitochondrial ATP production in dystrophin-deficient muscles

10:15

1110

Leah J. Harcourt, Paul Gregorevic, Nicole Stupka, David R. Plant, Gordon S. Lynch

Interleukin-15 administration improves diaphragm muscle function in dystrophic mdx mice

11:00

1118

Anna-Greer Holmes, Paul Gregorevic, Nicole Stupka, David R. Plant, Gordon S. Lynch

Short-term interleukin-15 treatment does not enhance functional repair following skeletal muscle injury

11:15

1119

Chris van der Poel, D. George Stephenson

Dithiothreitol effects on temperature-induced changes in the contractile activation characteristics of mammalian skeletal muscle as result of superoxide production

11:30

1120

James G. Ryall, David R. Plant, Paul Gregorevic, Gordon S. Lynch

Fenoterol treatment reverses sarcopenia and improves muscle function in aged rats

11:45

1121

Susan Bortolotto, Wayne Morrison, Aurora Messina

Ischaemia-reperfusion injury in skeletal muscles of mast cell deficient mice

12:00

1122

Yue-kun Ju, David G. Allen

The effects of metabolic inhibition on Na⁺/Ca²⁺ exchange current in toad pacemaker cells

12:15

1123

Angela F. Dulhunty, Suzi M. Pace, Suzanne M. Curtis, Magdolena Sakowska, Philip G. Board, Marco G. Casarotto

Are cardiac dihydropyridine receptors physically coupled to cardiac ryanodine receptors

11:00

1124

Judy L. Morris, Pat Vilimas, Keiko Mayne, Phillip Jobling, Toshihiko Shimizu, Ian L. Gibbins

Increased interleukin-1 receptor immunoreactivity in sympathetic neurons in guinea-pig coeliac ganglia incubated in vitro

11:15

1125

Shi-Yong Yuan, Simon J.H. Brookes, Marcello Costa

Pattern of pacemaker activity in the circular and longitudinal muscle layers of the guinea pig gastro-duodenal junction

11:30

1126

Claire L. Curl, Trudi Harris, Akram A. Kabbara, Brendan E. Allman, Ann Roberts, Keith A. Nugent, Peter J. Harris, Alastair G. Stewart, Lea M.D. Delbridge

Measurement of area changes in human airway smooth muscle cells using quantitative phase microscopy

11:45

1127

Imogen Arnold, M.J. McKinley, M.A. Febbraio, M.L. Mathai

Involvement of central nitrergic mechanisms in thermoregulation during heat stress and at room temperature

12:00

1128

Rafidah H. Mokhtar, Omar H. Kasule, Noriah M. Noor

Blood pressure variability and arterial elasticity in non insulin dependent diabetes mellitus subjects

2400

Kathryn Woolf-May, Andrew Owen, Deborah Ferrett, Steve Bird

The effectiveness of 18 weeks of accumulative short bouts of brisk walking upon left ventricular diastolic function?

2401

David R. Plant, Paul Gregorevic, Gordon S. Lynch

IGF-I treatment does not alter the contractile activation characteristics of single fibres from fast skeletal muscles of mdx mice

2402

Travis L. Dutka, Graham D. Lamb

Effect of low ATP concentrations on force relaxation in rat EDL muscle fibres

2403

Emma Rybalka, Michael F. Carey, Alan Hayes

Creatine supplementation improves sarcoplasmic reticulum function in dystrophic skeletal muscle

2404

Nicole Stupka, Paul Gregorevic, David R. Plant, Gordon S. Lynch

Inhibition of the calcineurin signalling pathway with cyclosporine A impairs muscle regeneration in young mdx mice

2405

Dale Bickham, Peter Le Rossignol, David Cameron-Smith

High-intensity interval training selectively increases the lactate transporter isoform mct1 in human skeletal muscle

2406

D. Martino, S. Fletcher, M. Grounds, S.D. Wilton

Transient suppression of the myostatin gene transcript - a comparison of different antisense nucleic acid mechanisms

2407

G.K. McConell, N.K. Stepto, Z-P. Chen, T.J. Stephens, N.N. Huynh, B.J. Canny, B.E. Kemp

Short-term exercise training suppresses increases in human skeletal muscle AMPK activity during prolonged exercise

2408

Amrita Unnikrishnan, Graham D. Lamb.

Effects of low cytoplasmic pH on excitation-contration coupling in rat skinned muscle fibres

2409

G.D. Wadley, C. Bruce, N. Konstantopoulos, L. Macauley, J. Hawley, M. Hargreaves, K. Howlett, D. Cameron-Smith

The effects of insulin or exercise on Cbl in lean and obese skeletal muscle

2410

Emily L. Mulholland, Billie Hunne, Craig B. Neylon, Richard J. Lang

Nitric oxide (NO*) donors increase the opening of native intestinal and cloned alpha subunits of human brain BK_Ca channels

2411

Esther M. Gallant, Suzanne Curtis, James Hart, Kevin Eager, Angela F. Dulhunty

Caffeine sensitivity of the native skeletal ryanodine-receptor from normal and malignant hyperthermic pigs

2412

Anna Kloda, Annette Nicke, R.J. Lewis, D.J. Adams

ATP inhibits current through recombinant NMDA receptors expressed in Xenopus oocytes

2413

Bonny N. Honen, Derek R. Laver, David A. Saint

Polyunsaturated fatty acids reduce the open probability of the cardiac ryanodine receptor

2414

Pierre Pouliquin, Susan Treves, Luca Moccagatta, Francesco Zorzato

How many and where are located the membrane spanning segments of the ryanodine receptor/calcium release channel?

2415

Grigori Y. Rychkov, M. Lyn Harland, Gregory J. Barritt

Modulation of the Ca²⁺ release activated Ca²⁺ channel by calmodulin

2416

Joy H.C. Tan, Weihong Liu, David A. Saint

Stretch-activated potassium channels in rat ventricular cells

2417

Andrea B Everitt, Tien Luu, Peter W Gage

GABARAP affects conductance of GABA_A receptors

2418

Charles M.S. Humphreys, Marcello Costa, Simon J.H. Brookes

Comparison of neural peristalsis in the guinea-pig duodenum, jejenum and ileum

2419

Ruchi Patel, Igor R. Wendt

Effect of hydrogen peroxide on intracellular calcium and force in rat anococcygeus muscle

2420

Eva Patak, Sebastian Ziccone, Jocelyn N. Pennefather, Margot E. Story, Alison Lilley

Uterotonic effects of eledoisin on pregnant human uterus are mediated by NK₂ receptors

2421

Nour Bishara, Michael Hill

Arachidonic acid-induced Ca²⁺ mobilization in cultured endothelial cells

2422

Hema Raina, Kerryn Popa, Simon Potocnik, Neela Kotecha, Alex Wiedenmann, Clemens Schneeweiss, Michael A. Hill

Na⁺/Ca²⁺ (NCX) exchange in myogenically active arterioles

2423

Chrishan S. Samuel, Chongxin Zhao, Ross A.D. Bathgate, Courtney P. Bond, Matthew D. Burton, Laura J. Parry, Roger J. Summers, Mimi L.K. Tang, Geoffrey W. Tregear

Relaxin: A potential therapy for pulmonary fibrosis

2424

Melanie Yeoh, Elspeth M. McLachlan, James A. Brock

Effects of decentralization of the sympathetic postganglionic supply on transmission to the rat tail artery

2425

Hala A. Raghib, Timothy V. Murphy, Harry Majewski

Effect of gender and ovariectomy on COX expression in rat aorta

2426

M.J. Watson

Nature of the rhythmic oscillations recorded at negative potentials in gastrointestinal smooth muscle

2427

Saxon White, Stephen McIlveen, Robert Bishop, Anthony Quail, David Cottee, Gibbe Parsons, Robert Gunther, Jessica Davis, Linda Talken

Mechanisms of bronchial blood flow response during and after exercise in sheep

2428

Junhua Xiao, Craig B. Neylon, John B. Furness

Oligophrenin-1, a rho-gap protein involved in central cognitive function, is expressed in specific neurons of the enteric nervous system

2429

Gemma M. O'Brien, Susan Arentz

Normalising reproductive physiology in the preconception period

2430

Susan Arentz, Gemma M. O'Brien

Improving reproductive physiology and fertility for people with abnormal body mass index

2431

Isabel Pons-Meneghetti, Martin Johnson, David Cook, Margot Day

CFTR in the pre-implantation embryo

2432

Nora Chen, Michael L. Mathai, Andrew J. Sinclair, Richard S. Weisinger, Harrison S. Weisinger

Perinatal dietary omega-3 fatty acid manipulation affects neural control of sodium homeostasis in adulthood

2433

Urszula Lorenc, Rachael O'Dowd, Irene Koukoulas, Karen Moritz, Angela Gibson, Patricia W.M. Ho, Jane M. Moseley, Mary E. Wlodek

Uteroplacental insufficiency impairs mammary function and perinatal growth: a cross fostering study

2434

Adrian D. Pearce, Nora Chen, Richard S. Weisinger, Andrew J. Sinclair, Harrison S. Weisinger

Perinatal supply of omega-3 fatty acids programs core body temperature later in life

2435

A. Azizi, Omar H. Kasule, Mazidah A. Mansur, Tariq A. Razak.

Effects of irbesartan, an angiotensin II antagonist, on plasma total homocysteine in malaysian hypertensive patients

2436

Abstract withdrawn

2437

Lele Jiang, Michelle Bardini, Cristobal G. dos Remedios, Geoffrey Burnstock

Expression and localization of the P2X₁ receptor in human ventricular myocardium

2438

Sandra Pollitt, Shelli Stocks, Ian Shiels, Alan Scott, Stephen Taylor

Development of a new class of anti-inflammatory drugs, small molecule C5a inhibitors

2439

Megan Smart, Rekha Panchal, Ben Gu, James Wiley, Brett Cromer, David Williams, Steven Petrou

A C-terminal region of the rat P2X7 Receptor determines cell surface expression

2440

K.A. Whyte, D.J. Adams

Effects of reactive oxygen species on neuronal excitability of intrinsic cardiac ganglia

2441

ZhuoWei Xiong, YeanLeng Lim, KoonHou Mak, Beryl M Biegler (Deceased), Nicholas D.H. Balazs, YiShen Junie H'ng, SimLeng Tien, SingZern Fong, TianHai Koh, Charles Chan, DingWei Xiong, Bridget H-H Hsu-Hage, Dong Wang, HeMing Wei, Subroto Chatterjee, Mark L Wahlqvist

Comparison of apolipoprotein(a) phenotypes in chinese women between living in Singapore and Australia

2442

Judy A. Craft, Neville A. Marsh

Increased generation of platelet-derived microparticles following percutaneous transluminal coronary angioplasty

2443

Alice A. Lim, Martin H. Johnson, Margot L. Day

Circadian gene expression in mouse reproductive tissues

2444

Alexander S. Nicholls, Lele Jiang, David G. Allen

Adenosine inhibits angiotensin II activation of the cardiac Na⁺/H⁺ exchanger in rat ventricular myocytes

2445

S.J. Jiang, Kh H.Haider, L. Ye, F.L. Chua, P.K.Law, J.T. Lu, E.K.W. Sim

Transient immunosuppression is effective for human myoblast xenograft for myocardial repair

2446

L. Ye, H. Haider, P.K. Law, M. Teh, T. Chua, P. Wong, Y.L. Lim, E.K.W. Sim

Angiomyogenesis using human myoblasts carrying hVEGF₁₆₅ for improved myocardial performance

2447

Monique Youssoufian, Ulrike Mathesius, Rosemary Martin

Mild, prenatal hypoxia in the pregnant rat induces alterations in the cardiorespiratory function and protein expression of juvenile offspring

2448

A.J. Camp, H-Y. Lee, R.J. Callister, A.M. Brichta

Responses of vestibular afferents to mechanical stimulation and drug application in mouse in vitro labyrinth

2:00

Dr David Williams

Introduction

2:05

124

Dr Miranda D. Grounds

School of Anatomy & Human Biology, the University of Western Australia

Effects of IGF-I over-expression on skeletal muscle denervation, ageing and damage

2:30

125

Dr Graham D. Lamb

Department of Zoology, La Trobe University, Victoria

Oxidation and the control of muscle contraction

3:00

126

Prof Uwe Proske

Department of Physiology, Monash University, Victoria

The mechanism of muscle damage from eccentric exercise: implications for sports medicine

3:30

127

Dr Gordon S. Lynch

Muscle Mechanics Laboratory, Department of Physiology, The University of Melbourne, Victoria

Improving muscle repair and function in the frail elderly

2:00

1148

Mohammad S. Imtiaz, Jun Zhao, Dirk F. van Helden

A theoretical study of Ca²⁺ oscillations and pacemaker potentials underlying vasomotion in guinea-pig lymphatic smooth muscle

2:15

1150

B. Exintaris , R.J. Lang .

Role of calcium stores in the generation of spontaneous activity in the prostate gland of the guinea-pig

2:30

1152

Igor R. Wendt, Hamdia Solaiman

Effects of gender and oestrogen on intracellular calcium and contractility of rat urinary bladder smooth muscle

2:45

1149

Jun Zhao, Mohammad S. Imtiaz, Dirk F. van Helden

Ca²⁺ oscillations and pacemaker potentials underlying vasomotion of guinea-pig lymphatic smooth muscle

3:00

1151

Neela Kotecha, Michael A. Hill

Arteriolar smooth muscle membrane potential and Ca_i²⁺ supply during myogenic contraction

3:15

1153

Ralph N. Watts, Des Richardson

The effects of nitric oxide on cellular iron metabolism

8:30

200

Dr Lea M.D. Delbridge

Department of Physiology, University of Melbourne, Parkville, Victoria

Hydrogen handling in cardiac hypertrophy - when bigger is not better

9:00

201

Prof David G. Allen

Department of Physiology and Institute for Biomedical Research, University of Sydney, NSW

Mechanisms of recovery after ischaemia in the heart

9:30

202

Dr Robert M. Graham

Victor Chang Cardiac Research Institute, Darlinghurst, NSW

Molecular mechanisms of inherited cardiomyopathies

10:00

203

Prof Morris Karmazyn

Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario N6A 5C1, Canada

Role of Na-H exchange (NHE-1) in myocardial ischaemia and hypertrophy

8:30

1208

Amanda C. Boyce, Karen J. Gibson, Eugenie R. Lumbers

Stimulation of the circulating renin-angiotensin system by chronic hypoglycaemia in late gestation fetal sheep

8:45

1209

K.E. Warnes, C.L. Coulter, J.S. Robinson, I.C. McMillen

The effect of metyrapone infusion on arterial blood pressure in the late gestation fetal sheep

9:00

1210

Karen J. Gibson, Bilal M. Karime, Yiping Zhou, Amanda C. Boyce, Eugenie R. Lumbers

Effects of maternal subtotal nephrectomy prior to mating on the development and function of the ovine fetal kidney

9:15

1211

D.A. Grant, J-C. Fauchère, J.J. Wang, J.V. Tyberg, A.M. Walker

Birth related changes in the interaction between the right ventricle and the pulmonary vasculature

9:30

1212

N. Loos, D. Grant, J. Wild, S. Paul, C. Barfield, A. Walker

Sympathetic control of the cerebral circulation in sleeping newborn lambs

9:45

1213

Eugenie R. Lumbers, Ze-Yan Yu

Fetal renal sympathetic nerve activity, behavioural state and regulation of the fetal cardiovascular system

10:00

1214

Judith H. Burrell, Adrian M. Boyn, Vasumathy Kumarasamy, Albert Hsieh, Stewart I. Head, Eugenie R. Lumbers.

Maturation of cardiac myocytes in fetal and newborn sheep: A study examining changes in myocyte nuclear number and volume

10:15

1215

H.Liu, A.Armugan, K.Jeyaseelan, S.Hooper, I.Koukoulas, E.M.Wintour

Ontogeny and regulation of aquaporin expression in the ovine fetal lung

8:30a

1216

Gail Kasiri, Steve Bird, James Balmer, Michael Gleeson

Effect of a single bout of moderate intensity exercise on levels of salivary immunoglobulin a in women exercisers

8:45

1217

Mark Hargreaves, Yorgos N. Kraniou, David Cameron-Smith

Acute exercise and glut-4 expression in human skeletal muscle: influence of exercise intensity

9:00

1218

Matthew B. Cooke, Graeme Smith, Michael F. Carey, Alan Hayes

The effects of dietary supplements whey protein and creatine on strength and fatiguabilty in rat skeletal muscle

9:15

1219

Mark A. Febbraio, Adam Steensberg, Charlotte Keller, Rebecca L. Starkie, Henning B. Nielsen, Peter Krustrup, Peter Ott, Niels H. Secher, Bente K. Pedersen

Increasing extracellular glucose attenuates IL-6 release from, but not expression within, contracting human skeletal muscle

9:30

1220

Andrew L. Carey, Clinton R. Bruce, Mitchell J. Anderson, John A. Hawley, Mark A. Febbraio

Neither circulating IL-6 nor skeletal muscle IL-6 mRNA are predictors of insulin resistance during a hyperinsulinemic clamp in humans

9:45

1221

Sean L. McGee, Kirsten F. Howlett, Rebecca L. Starkie, David Cameron-Smith, Bruce E. Kemp, Mark Hargreaves

Exercise increases nuclear AMPK abundance in human skeletal muscle

10:00

1222

Leanne M. Redman, Robert J. Norman, G.C. Scroop

Impact of phase of the menstrual cycle on the lactate threshold

10:15

1223

Graeme J. Smith, Matthew B. Cooke, Andrew D. Williams, Alan Hayes, Michael F. Carey

The effects of dietary supplements creatine and whey protein on indices of muscle oxidative capacity

2:00

Prof Mark Hargreaves

Introduction

2:05

236

Prof David E. Kelley

Obesity and Nutrition Research Centre, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA

The role of skeletal muscle in the metabolic syndrome

3:00

237

Dr Kirsten F. Howlett

Exercise, Muscle and Metabolism Unit, School of Health Sciences, Deakin University, Victoria

Exercise and skeletal muscle insulin signalling

3:30

238

Dr Mark A. Febbraio

Skeletal Muscle Research Laboratory, School of Medical Sciences, RMIT University, Bundoora, Victoria

Muscle derived interleukin-6: role in health and disease

2:00

Prof D.I. Cook

Introduction

2:10

239

Dr Anuwat Dinudom

Department of Physiology, University of Sydney

Na⁺ feedback regulation of the epithelial Na⁺ channel: roles of the uniquitin protein-ligases Nedd4 and Nedd4-2

2:35

240

Dr Karl Kunzelmann

Department of Physiology and Pharmacology, University of Queensland, St. Lucia, Queensland

Cystic fibrosis; CFTR and the defect in membrane transport

3:00

241

Dr A.K.M. Hammarström

John Curtin School of Medical Research, Australian National University, Canberra

Hypoxia and misbehaving sodium channels

3:25

242

Dr Joseph W. Lynch

Department of Physiology and Pharmacology, School of Biomedical Sciences, University of Queensland, Brisbane

Insights into glycine receptor structure and function from startle disease mutations

8:30

300

Prof David Phillips

University of Southampton, UK

Small babies, stress hormones and disease in adult life

9:00

301

Prof I.C. McMillen

Department of Physiology, University of Adelaide, Adelaide, SA

Fetal fat, leptin and the programming of adult obesity

9:30

302

Prof Eugenie R. Lumbers

Department of Physiology & Pharmacology, School of Medical Sciences, University of New South Wales, Sydney, NSW

Fetal orgins of hypertension and the developing renin angiotensin system

10:00

303

Dr Julie Owens

Department of Physiology, Research Centre for the Physiology of Early Development, University of Adelaide, Adelaide, SA.

Fetal and postnatal growth and the origins of adult diabetes

8:30

1323

D.J.S. Lee, A. Keramidas, A.J. Moorhouse, K.D. Pierce, P.R. Schofield, P.H. Barry

The minimum pore diameter of the m2 p-2'Δ mutation in the α1 glycine receptor gives further insight into factors controlling glycine receptor ion charge selectivity

8:45

1324

Yasser Abdellatif, Do Han Kim

Kinetic studies of the effect of FKBP12 on the ryanodine receptor from skeletal muscle sarcoplasmic reticulum

9:00

1325

A. Keramidas, A.J. Moorhouse, M. O'Mara, K.D. Pierce, P.R. Schofield, S-H Chung, P.H. Barry.

M2 mutations, which switch the ion selectivity of glycine receptor channels and act via both electrostatic effects and changes in minimum pore diameter, and mathematical modelling

9:15

1326

B. Bennetts, M.L. Roberts, A.H. Bretag, G.Y. Rychkov

Ionic selectivity of ClC-0 chloride channel

9:30

1327

Michael Duffield, Grigori Rychkov, Allan Bretag, Michael Roberts

Effect of G, H and I domain mutations on ClC-1 slow gating

9:45

1328

Damien J. Keating, Grigori Y. Rychkov, Michael B. Adams, Hans Holgert, Caroline McMillen, Michael L. Roberts

μ-opioid receptor stimulation suppresses the direct hypoxic response in ovine adrenal chromaffin cells by actions on Ca²⁺ and K⁺ channels

10:00

1329

Weiping Wu, Grigori Rychkov, Allan Bretag, Bernie Hughes

Reconstitution of function in CLC-1: co-expression of its transmembrane domain and small fragments of its C-tail

10:15

1330

Anastasia S. Mihailidou, Mahidi Mardini, Tafline Fraser, John W. Funder

PKCε mediates rapid aldosterone-induced activation of sarcolemmal Na⁺/K⁺/2Cl^- cotransport

2:00

Prof Don Robertson

Introduction

2:05

337

Boris Martinac

Department of Pharmacology, Queen Elizabeth Ii Medical Center, University of Western Australia, Crawley, WA

Molecular structure of mechanosensitive channels

2:35

338

Prof Tony Gummer

University of Tübingen, Germany

Mechanotransduction in cochlear outer hair cells

3:05

339

R. Patuzzi

Department of Physiology, School of Biomedical and Chemical Sciences, The University of Western Australia

Nonlinear and kinetic aspects of channels gating and their role in audition

3:25

340

Alan M. Brichta

School of Biomedical Sciences, Faculty of Health, University of Newcastle, Callaghan, N.S.W

Transduction in vestibular sense organs

3:45

341

James B. Fallon

Department of Electrical and Computer Systems Engineering, Monash University, Victoria

Stochastic resonance in mechanoreceptors

2:00

1358

Giuseppe S. Posterino, Graham. D. Lamb

Effect of sarcoplasmic reticulum Ca²⁺ content on the total amount of Ca²⁺ released during a single twitch

2:15

1359

Gunther H. Rossmanith

Simulation of the development of isometric muscle force in response to calcium

2:30

1360

David R. Plant, Gordon S. Lynch

Depolarization-induced contraction and sr function in mechanically skinned fast muscle fibres from dystrophic mdx mice

2:45

1361

Anthony J. Bakker, Renzhi Han, Miranda D. Grounds, Takuya Suizu

The effect of the phospholipase a₂ inhibitors indomethacin and quinacrine on depolarisation-induced force responses in skinned skeletal muscle fibres of the rat

3:00

1362

C.J. Barclay

Cardiac cross-bridges operate with similar efficiency to those in other striated muscles

3:15

1363

Ella W. Yeung, David G. Allen

Changes in intracellular sodium following eccentric contractions in mouse skeletal muscle