AuPS Melbourne 2008 Meeting

In the programme below, each presentation has, beside the presentation time or poster board, the page number in volume 39 of the Proceedings. These numbers are links to the HTML versions of the pages. Each HTML page has a link to a corresponding PDF print version.

A PDF file of the abstracts for each platform and poster session can be accessed by clicking on the PDF symbol in the upper right of the programme block.

Links to the abstracts can also be found in the full author index and in the presenting author index.

Posters will be available for viewing througout the meeting. Presenting authors will be at their poster duing the poster session on Tuesday. Odd numbered posters will be manned from 1330-1430; even numbered ones from 1430-1530.

Sunday 30 November 2008

Wright Theatre

Plenary Lecture &mdash Lars Larsson

Chair: Gordon Lynch

1700	1P	Regulation of human muscle contraction in health and disease — L. Larsson, Department of Clinical Neurophysiology, Uppsala University, Sweden, and Center for Development and Health Genetics, Penn State University, Pennsylvania, USA.
1800		Close

1800-2000 Welcome reception - Alan Gilbert Building, Executive Lounge

Monday 1 December 2008

King Theatre

Symposium: Signaling in Cell Secretion

Chair: Chen Chen and Peter Thorn

0830	2P	Complex interactions between ghrelin and obestatin in the regulation of GH secretion and food intake — J. Epelbaum, UMR 894 Inserm, Faculté de Médecine, Université Paris Descartes, Centre de Psychiatrie et Neuroscience, 2 ter rue d’Alésia, 725014 Paris, France. (Introduced by C. Chen)
0900	3P	The behaviour and control of post exocytic vesicles — P. Thorn and P. Bhat, School of Biomedical Sciences, The University of Queensland, QLD 4072, Australia.
0930	4P	Integrating studies of proteins and lipids: dissecting the mechanism of Ca²⁺-triggered membrane fusion — J.R. Coorssen, Molecular Physiology, School of Medicine, University of Western Sydney, Campbelltown Campus, NSW 2570, Australia. (Introduced by C. Chen)
1000	5P	Receptor- and metabolite-mediated increase in [Ca²⁺]_i in rat pancreatic islet cells by free fatty acids — C. Chen and Y. Zhao, School of Biomedical Sciences, University of Queensland, Brisbane, QLD 4072, Australia.
1030		Close

Wright Theatre

Symposium: Myopathies and Muscle Regeneration

Chair: Gordon Lynch

0830	6P	Using gene transfer technology to study muscle diseases — P. Gregorevic, Laboratory for Muscle Research & Therapeutics Development, Baker IDI Heart and Diabetes Institute, Melbourne, VIC 3004, Australia.
0900	7P	Muscle hypertrophy and IGF-1 isoforms: is bigger better? — T. Shavlakadze,¹ R. Chai,¹ G.J. Pinniger,¹ K. Maley,¹ G. Grounds,¹ N. Winn,² N. Rosenthal² and M.D. Grounds,¹ ¹School of Anatomy and Human Biology, University of Western Australia, WA 6009, Australia and ²Mouse Biology Unit, EMBL Monterotondo Outstation, via Ramarini 32, 00016, Monterotondo, Rome, Italy.
0930	8P	Novel regeneration in nemaline myopathy — A.J. Kee,^1,2 J. Joya,¹ V. Nair-Shalliker,¹ M.A. Nguyen¹ and E.H. Hardeman,³ ¹Muscle Development Unit, Children’s Medical Research Institute, Westmead, NSW 2145, Australia, ²Faculty of Medicine, University of Sydney, NSW 2006, Australia and ³Department of Anatomy, School of Medical Science, University of New South Wales, Kensington, NSW 2052, Australia.
1000	9P	Acute Quadriplegic Myopathy and myosin loss in ICU patients: Underlying mechanisms, improved diagnostics and a specific intervention strategy — L. Larsson,^1,3 J. Ochala,¹ V. Banduseela,¹ A-M. Gustafsson,¹ P. Radell,² L.I. Eriksson² and B. Dworkin,¹ ¹Department of Clinical Neurophysiology, Uppsala University, Sweden, ²Dept of Anaesthesia and Intensive Care, Karolinska Institute, Sweden and ³Department of Neuroscience and Center for Development and Health Genetics, Penn State University, Pennsylvania, U.S.A. (Introduced by G.S. Lynch)
1030		Close

Morning Tea - Alan Gilbert Building

King Theatre

Symposium: Regulation of Trafficking of Membrane Transporters by Intracellular Signaling Systems

Chair: David Cook

1100	10P	New insights into the formation and function of caveolae — R.G. Parton, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland 4072, Australia. (Introduced by D.I. Cook)
1130	11P	Regulation of receptors, transporters and ion channels by the Nedd4 family of ubiquitin ligases — S. Kumar,^1,6 N. Boase,¹ B. Yang,² R. Daly,³ S. Townley,¹ A. Dinudom,⁴ D.I. Cook,⁴ P. Poronnik⁵ and G.Y. Rychkov,⁶ ¹Hanson Institute, IMVS, SA 5000, Australia, ²Department of Obsterics and Gynecology, University of Iowa, IA 52242, USA, ³Garvan Institute, Sydney, NSW 2010, Australia, ⁴Dicipline of Physiology, Faculty of Medicine, University of Sydney, NSW 2006, Australia, ⁵School of Biomedical Sciences, University of Queensland, QL 4067, Australia and ⁶Discipline of Physiology, School of Molecular and Biomedical Sciences, University of Adelaide, SA 5005, Australia.
1200	12P	The role of phospholipids in controlling GLUT4 exocytosis — W.E. Hughes, Garvan Institute, 384 Victoria Street, Darlinghurst, NSW 2010, Australia. (Introduced by Anuwat Dinudom)
1230	13P	The physiological roles of sulfate transporters — D. Markovich, School of Biomedical Sciences, University of Queensland, St. Lucia, QLD 4072, Australia.
1300		Close

Wright Theatre

Free communications: Muscle

Chair: Anthony Bakker

1100	14P	The effects of arsenic on the two major fibre types in the chelae of the freshwater crayfish Cherax destructor (Clarke) — G. Williams and J.M. West, School of Life and Environmental Sciences, Deakin University, 221 Burwood Hwy, Burwood, VIC 3125, Australia.
1115	15P	Development of the diaphragm and the effects of maternal creatine supplementation on birth hypoxia in a novel precocial species, the spiny mouse (Acomys cahirinus) — D. Cannata,¹ Z. Ireland,² H. Dickinson,³ D.W. Walker² and J.M. West,¹ ¹School of Life and Environmental Sciences, Deakin University, 221 Burwood Hwy, Burwood,VIC 3125, Australia, ²Department of Physiology, Monash University, Clayton, VIC 3168, Australia and ³Monash Immunology & Stem Cell Laboratories, Monash University, Clayton, VIC 3168, Australia.
1130	16P	Unique actions of junctin and triadin on skeletal muscle ryanodine receptor calcium release channels — L. Wei, A.F. Dulhunty and N.A. Beard, Muscle Research Group, The John Curtain School of Medical Research, The Australian National University, Canberra, ACT 0200, Australia..
1145	17P	The force-generating attachment of myosin heads (cross-bridges) to the actin filaments is controlled differently in fast- and slow-muscle fibre types — D.G. Stephenson,¹ O. Andruchov,² G.M.M. Stephenson³ and S. Galler,² ¹Department of Zoology, La Trobe University, Vic 3086, Australia, ²Department of Cell Biology, University of Salzburg, A-5020, Austria and ³Muscle Cell Biochemistry Laboratory, School of Biomedical and Health Sciences Victoria University, VIC 8001, Australia.
1200	18P	Conformational coupling of store-operated Ca²⁺ entry in skeletal muscle — B.S. Launikonis, J.N. Edwards, F. von Wegner and O. Friedrich, School of Biomedical Sciences, University of Queensland, St Lucia, Qld 4072, Australia.
1215	19P	Store-operated Ca²⁺ entry in dystrophic skeletal muscle is not a source for Ca²⁺ overload due to robust deactivation — O. Friedrich,¹ J.N. Edwards,¹ R.M. Murphy² and B.S. Launikonis,¹ ¹University of Queensland, School of Biomedical Sciences, St Lucia campus, Brisbane, QLD 4072, Australia and ²La Trobe University, Bundoora campus, Department of Zoology, Melbourne, VIC 3086, Australia.
1230	20P	Calcium transients in fast-twitch FDB skeletal muscle from old dystrophic mice — S.I. Head, Department of Physiology, University of New South Wales, Sydney, NSW 2052, Australia.
1245	21P	Blocking TNF (using cV1q) reduces the severity of stretch-induced muscle damage in dystrophic, mdx mice — A.T. Piers,^1,2 A.J. Bakker,¹ H.G. Radley,² M.D. Grounds² and G.J. Pinniger,¹ ¹School of Biomedical, Biomolecular and Chemical Sciences, University of Western Austalia, WA 6009, Australia and ²School of Anatomy and Human Biology, University of Western Austalia, WA 6009, Australia.
1300		Close

1300-1400 Lunch

King Theatre

Free communications: Ion Channels

Chair: Alan Bretag

1400	22P	Effect of volatile anaesthetics on the calcium release channel in the heart — D.R. Laver, T. Quail, H. Sitsapesan and D.F. van Helden, School of Biomedical Sciences, University of Newcastle and Hunter Medical Research Institute, Callaghan, NSW 2308, Australia.
1415	23P	The role of depolarising and repolarising currents in the induction of early afterdepolarisations during acute hypoxia in ventricular myocytes — W.A. Macdonald,¹ N. Gaur,² Y. Rudy² and L.C. Hool,¹ ¹School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, Crawley, WA 6009, Australia and ²Cardiac Bioelectricity and Arrhythmia Center, Washington University, St Louis, MO 63130-4899, USA.
1430	24P	Ageing related change in store-operated Ca2⁺ influx and TRPCs expression of sinoatrial node — Y.K. Ju, D. Lai and D.G. Allen, School of Medical Sciences, Bosch institute, University of Sydney, NSW 2006, Australia.
1445	25P	Delineating the gating pathway in the α1 glycine receptor ligand-binding domain — S.A. Pless and J.W. Lynch, Queensland Brain Institute and School of Biomedical Sciences, University of Queensland, Brisbane, QLD 4072, Australia..
1500	26P	External divalent ions increase anion-cation permeability in glycine receptor channels – consideration of ion activities, surface charge and conductance measurements — P.H. Barry,¹ S. Sugiharto,¹ J.E. Carland,¹ T.M. Lewis,¹ P.R. Schofield² and A.M. Moorhouse,¹ ¹Department of Physiology and Pharmacology, School of Medical Sciences, University of New South Wales, NSW 2052, Australia and ²The Prince of Wales Medical Research Institute, Barker Street, Randwick, NSW 2031, Australia.
1515	27P	FRET study of C-terminal movements of the cytoplasmic tail of human skeletal muscle chloride channel, hClC-1, during gating — L. Ma,^1,2 G.Y. Rychkov,² E.A. Bykova,³ J. Zheng³ and A.H. Bretag,¹ ¹Sansom Institute, University of South Australia, North Terrace, Adelaide, SA 5000, Australia, ²Physiology Discipline, School of Molecular and Biomedical Science, University of Adelaide, SA 5005, Australia and ³Department of Physiology and Membrane Biology, University of California at Davis, Davis, CA 95616, USA.
1530	28P	Neonatal hypoxia increases hippocampal excitability in adulthood: Gender differences and prevention by neurosteroid treatment — H.A. Coleman,¹ C. Moller,¹ T. Yawno,¹ D.W. Walker,¹ D.C. Reutens² and H.C. Parkington,¹ ¹Department of Physiology, Monash University, Clayton Vic 3800, Australia and ²Department of Medicine, Monash Medical Centre, Clayton Road, Clayton Vic 3168, Australia.
1545	29P	A quantifiable approach to filtering and analysis of cellular fluorescence imaging — J.L. Bourke,¹ H. Hashitani,² H. Suzuki² and R.J. Lang,¹ ¹Department of Physiology, Monash University, Victoria 3800, Australia and ²Department of Regulatory Cell Physiology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan.
1600		Close

Wright Theatre

Symposium: Skeletal Muscle: an Endocrine Organ

Chair: Mark Febbraio

1400	30P	PGC-1α in muscle links metabolism to inflammation — C. Handschin, University of Zurich, Institute of Physiology and Zurich Center for Integrative Human Physiology (ZIHP), Winterthurerstrasse 190, CH-8057 Zurich, Switzerland. (Introduced by Mark Febbraio)
1440	31P	Role of protease-activated receptors (PARs) in muscle inflammation and cytokine release — A.J. Bakker, K.A. Burlinson, G.J. Pinniger, N. Asokananthan and G.A. Stewart, School of Biomedical, Biomolecular & Chemical Sciences, University of Western Australia, WA 6009, Australia.
1520	32P	Myokines and metabolic regulation — M.A. Febbraio¹ and B.K. Pedersen,² ¹Cellular & Molecular Metabolism Laboratory, Division of Metabolism & Obesity, Baker IDI Heart & Diabetes Institute, 75 Commercial Rd, Melbourne, VIC 3004, Australia. and ²Centre of Inflammation and Metabolism, Rigshospitalet - Section 7641, Blegdamsvej 9, DK-2100, Copenhagen, Denmark.
1600		Close

1600-1630 Afternoon Tea - Alan Gilbert Building

King Theatre

Free Communications: Cardiovascular/Kidney

Chair: Livia Hool

1630	33P	Cardiac hypertrophy and oxidative stress are associated with insulin resistance in fructose fed mice — K.M. Mellor,¹ R.H. Ritchie² and L.M.D. Delbridge,¹ ¹Department of Physiology, University of Melbourne, VIC 3010, Australia and ²Heart Failure Pharmacology, Baker IDI Heart & Diabetes Institute, Melbourne, VIC 3004, Australia.
1645	34P	Comparison of anoxic tolerance of isolated cardiac myocytes from male and female rats — I.R. Wendt,^1,2 M. Vila Petroff,^1,3 C.L. Curl,¹ J.R. Bell,¹ A. Mattiazzi³ and L.M.D. Delbridge,¹ ¹Department of Physiology, The University of Melbourne, VIC 3010, Australia, ²Department of Physiology, Monash University, VIC 3080, Australia and ³Facultad de Ciencias Médicas, Centro de Investigaciones Cardiovasculares, UNLP, Argentina.
1700	35P	The Hypertrophic Heart Rat (HHR) exhibits enhanced myocardial PI3-K mediated signalling in the neonate, but not in the adult — J.R. Bell, E.R. Porrello, S.B. Harrap and L.M.D. Delbridge, Department of Physiology, The University of Melbourne, VIC 3010, Australia.
1715	36P	Mechanisms maintaining kidney tissue oxygenation during renal ischaemia in anaesthetised rabbits — R.G. Evans,¹ S. Michaels,¹ G.A. Eppel,¹ S.L. Burke,² G.A. Head,² J.F. Carroll³ and P.M. O'Connor,⁴ ¹Department of Physiology, Monash University, Victoria 3800, Australia, ²Baker IDI Heart and Diabetes Institute, Melbourne, Victoria 8008, Australia, ³Department of Integrative Physiology, University of North Texas Health Science Center, Fort Worth, Texas 76107, USA and ⁴Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53202, USA.
1730	37P	Computational modelling of oxygen transport in the whole kidney — B.S. Gardiner,¹ R.G. Evans,² P.M. O'Connor³ and D.W. Smith,^1,4 ¹Department of Civil and Environmental Engineering, The University of Melbourne, Melbourne, VIC 3010, Australia, ²Department of Physiology, Monash University, Melbourne, VIC 3800, Australia, ³Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA and ⁴Faculty of Engineering, Computing and Mathematics, University of Western Australia, Perth, WA 6009, Australia.
1745		Close

Wright Theatre

Free communications: Exercise

Chair: Mike McKenna

1630	38P	Can the increase in mitochondrial biogenesis in skeletal muscle following acute exercise be prevented by antioxidant supplementation? — G.D. Wadley, J. Bloom, A. Jamieson, J. Owen, D. Tait and G.K. McConell, Department of Physiology, The University of Melbourne, Parkville, VIC 3010, Australia.
1645	39P	Aberrent skeletal muscle mitochondrial responses to exercise in overweight women with polycystic ovary syndrome (PCOS) — N.K. Stepto,^1,2,3 D. Rachon,^2,4 C. Harrison,^2,3 S. Hutchison,² B. Strauss,⁵ M. Cooper,⁶ R. Southgate,⁶ C. Bruce,⁶ M.A. Febbraio⁶ and H.J. Teede,² ¹Centre for Ageing Rehabilitation Exercise and Sport, Victoria University, Melbourne, VIC 8001, Australia, ²Jean Hailes Foundation for Women’s Health Research Group, Centre for Womens Health, Monash Institute of Health Research, Clayton, VIC 3168, Australia, ³Department of Physiology, Monash University Clayton, VIC 3800, Australia, ⁴Department of Clinical Nutrition, Medical University of Gdańsk, Gdańsk, Poland, ⁵Clinical Nutrition & Metabolism, Monash Medical Centre Southern Health, Clayton, VIC 3800, Australia and ⁶Cellular and Molecular Metabolism Laboratory, Baker Research Institute, Melbourne, VIC 3181, Australia.
1700	40P	Effects of antioxidant supplementation and exercise training on skeletal muscle antioxidant enzymes and mitochondrial biogenesis — N.A. Strobel,¹ J.M. Peake,¹ A. Matsumoto,¹ S.A. Marsh,² J.S. Coombes¹ and G.D. Wadley,³ ¹School of Human Movement Studies, The University of Queensland, St Lucia, QLD 4072, Australia, ²Department of Nutrition and Exercise Metabolism, Washington State University, PO Box 1495, Spokane, WA 99210-1495, USA and ³Department of Physiology, The University of Melbourne, Parkville, VIC 3010, Australia.
1715	41P	Nitric oxide and ROS regulate skeletal muscle glucose uptake during contraction independent of AMPK α2 — T.L. Merry,¹ G.R. Steinberg,² G.S. Lynch¹ and G.K. McConell,¹ ¹Department of Physiology, The University of Melbourne, VIC 3010, Australia and ²St. Vincent's Institute of Medical Research, Fitzroy, VIC 3065, Australia.
1730	42P	Iron overload in skeletal muscle; redox stress and exercise capacity — T.F. Reardon and D.G. Allen, School of Medical Sciences (F13), Bosch Institute, The University of Sydney, NSW 2006, Australia.
1745	43P	The effect of continuous vs intermittent exercise on substrate utilization during exercise and recovery in healthy adults — M.L. Borg, C.G. Stathis and A. Hayes, Exercise Metabolism Unit, School of Biomedical and Health Sciences, Victoria University, Footscray, Victoria 3011, Australia.
1800		Close

King Theatre

Student symposium: Beyond your PhD

Chair: Stefan Gehrig

1800	44P	Beyond your PhD: Key considerations in planning your post-doctoral career path — P. Gregorevic, Laboratory for Muscle Research & Therapeutics Development, BakerIDI Heart and Diabetes Institute Melbourne, VIC 3004, Australia.
1900		Close

1930-late Student Mixer - Redback Brewery Hotel, 75 Flemington Road, North Melbourne

Tuesday 2 December 2008

King Theatre

Symposium: Signaling in Smooth Muscles

Chair: James Brock and Dirk van Helden

0830	45P	Ca²⁺ phase waves - a fundamental mechanism underlying propagation of gastric slow waves — D.F. van Helden, D.R. Laver and M.S. Imtiaz, School of Biomedical Sciences and Hunter Medical Research Institute, Faculty of Health, University of Newcastle, NSW 2308, Australia.
0900	46P	Molecular and biophysical properties of smooth muscle-type voltage-gated Na⁺ channels — N. Teramoto, Department of Pharmacology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan. (Introduced by Dr James Brock)
0930	47P	Spontaneous electrical and Ca²⁺ signals in the mouse renal pelvis that drive pyeloureteric peristalsis — R.J. Lang,¹ H. Hashitani,² M.A. Tonta,¹ J.L. Bourke,¹ H.C. Parkington¹ and H. Suzuki,² ¹Department of Physiology, School of Biomedical Sciences, Monash University, Clayton, Vic 3800, Australia and ²Department of Regulatory Cell Physiology, Nagoya City University Grad School, Nagoya 467-8601, Japan.
1000	48P	Do K⁺ channels play a role in noradrenergic signalling in vascular smooth muscle? — J.A. Brock and N.M. Rummery, Prince of Wales Medical Research Institute, Sydney, NSW 2031, Australia..
1030		Close

Wright Theatre

Symposium: Signals Mediating Exercise-Induced Skeletal Muscle Remodelling

Chair: Mark Hargreaves

0830	49P	Histone modifications and skeletal muscle metabolic gene expression — S.L. McGee, Department of Physiology, The University of Melbourne, VIC 3010, Australia.
0900	50P	Molecular regulation of skeletal muscle mass — A.P. Russell, The Centre for Physical Activity and Nutrition Research (C-PAN), School of Exercise and Nutrition Sciences, Deakin University, VIC 3125, Australia.
0930	51P	Calpains and skeletal muscle function — R.M. Murphy and G.D. Lamb, Department of Zoology, La Trobe University, Melbourne, VIC 3086, Australia.
1000	52P	A novel role for β-adrenoceptor signalling in the regulation of skeletal muscle mass — J.G. Ryall and G.S. Lynch, Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, VIC 3010, Australia.
1030		Close

1030-1100 Morning Tea - Alan Gilbert Building

King Theatre

Symposium: Ion Channels as Therapeutic Targets for Multiple Diseases

Chair: David Adams

1100	53P	Novel approaches for screening sodium channel function in drug discovery — S. Petrou, E.A. Thomas and B.B. Scaf, Howard Florey Institute, The University of Melbourne, VIC 3010, Australia.
1130	54P	Translational promise and physiological insights in Aquaporin drug discovery — A.J. Yool, Discipline of Physiology, School of Molecular & Biomedical Science, University of Adelaide, Adelaide, SA 5005, Australia.
1200	55P	The capsaicin receptor, TRPV1, as a target for chronic pain therapy — A. Bhaskaracharya,¹ H-J. Cho,² E. Jennings,² J. Ziogas¹ and P. McIntyre,¹ ¹Department of Pharmacology, University of Melbourne and ²Department of Anatomy and Cell Biology, University of Melbourne, Melbourne, VIC 3010, Australia. (Introduced by David Adams)
1230	56P	The P2X7 receptor and its genetic variants; relation to mood disorders — J.S. Wiley, L. Stokes, S.J. Fuller, R. Sluyter, K.K. Skarratt and B.J. Gu, Department of Medicine, University of Sydney, Nepean Hospital, Penrith, NSW 2750, Australia. (Introduced by David Adams)
1300		Close

Wright Theatre

Free communications: Metabolism and Signalling

Chair: Sean McGee

1100	57P	The role of an endogenous regulator of calcineurin in the regulation of glucose homeostasis — H.S. Peiris and D.J. Keating, Molecular and Cellular Neuroscience Group, Department of Human Physiology and Center for Neuroscience, Flinders Univeristy, Adelaide, SA 5001, Australia.
1115	58P	Acute stimulation of fatty acid oxidation does not alter energy expenditure — N. Turner, E. Preston, D. Wilks, M.M. Swarbrick, B.D. Hegarty, E.W. Kraegen and G.J. Cooney, Diabetes & Obesity Research Program, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia.
1130	59P	Glucose and insulin modulate the expression and activity of the thioredoxin antioxidant system in cultured human skeletal muscle fibres — N. Stupka,¹ S.D. Martin,¹ J.M. McKenzie,¹ F.M. Collier² and N. Konstantopoulos,³ ¹Institute of Biotechnology, Deakin University, Waurn Ponds, VIC 3217, Australia, ²Barwon Biomedical Research, Barwon Health, Geelong, VIC 3220, Australia and ³Metabolic Research Unit, Deakin University, Waurn Ponds, VIC 3217, Australia.
1145	60P	Role of nitric oxide in mitochondrial biogenesis in L6 myocytes — G.P.Y. Ng,¹ M. Phillips,¹ L. Macaulay,² G.D. Wadley¹ and G.K. McConell,¹ ¹Department of Physiology, University of Melbourne, Parkville, VIC 3010, Australia and ²Obesity and Diabetes Treatment Laboratory, CSIRO, Parkville, VIC 3010, Australia.
1200	61P	Effects of simvastatin on skeletal muscle mitochondrial biogenesis and mitochondrial enzyme activities — D.J. Pol,¹ P.K. Kennedy,² G.K. McConell¹ and C.A. Goodman,¹ ¹Department of Physiology, University of Melbourne, VIC 3010, Australia and ²State Neuropathology Service, Department of Pathology, University of Melbourne, VIC 3010, Australia.
1215	62P	Ingestion of a protein hydrolysate is accompanied by an accelerated in vivo digestion and absorption rate when compared with its intact protein — R. Koopman,^1,2 S. Walrand,³ A.K. Kies,⁴ W.H.M. Saris,¹ Y. Boirie³ and L.J.C. van Loon,¹ ¹Nutrition and Toxicology Research Institute Maastricht (NUTRIM), Maastricht University, Maastricht, The Netherlands, ²Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, VIC 3010, Australia, ³Université Clermont Auvergne, Centre de Recherche en Nutrition Humaine, Clermont-Ferrand Cedex 1, France and ⁴DSM Food Specialties, R&D, Biochemistry and Nutrition Department, Delft, The Netherlands.
1230	63P	Local insulin-like growth factor binding proteins are essential for successful skeletal muscle regeneration — S.M. Gehrig, J.D. Schertzer, J.E. Church and G.S. Lynch, Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, VIC 3010, Australia.
1245	64P	Human sarcopenia reveals an increase in SOCS-3 and myostatin and a reduced efficiency of Akt phosphorylation — B. Léger,¹ W. Derave,² K. De Bock,³ P. Hespel⁴ and A.P. Russell,⁵ ¹Clinique romande de réadaptation SuvaCare, Sion 1951, Switzerland, ²Institut de recherche en réadaptation-réinsertion, Sion 1951, Switzerland, ³Research Centre for Exercise and Health, Faculty of Kinesiology and Rehabilitation Sciences, K.U. Leuven, B-3001, Belgium, ⁴Department of Movement and Sport Sciences, Ghent University, Ghent, Belgium and ⁵The Centre for Physical Activity and Nutrition Research (C-PAN), School of Exercise and Nutrition Sciences, Deakin University, VIC 3125, Australia..
1300		Close

Alan Gilbert Building

Lunch and Posters

1300		Session opens
1	65P	PGC-1α reduces proteasome and lysosome activity and attenuates myotube protein degradation — P. Sepulveda, M.J. Quick, M.A. Wallace, R.J. Snow and A.P. Russell, The Centre for Physical Activity and Nutrition Research (C-PAN), School of Exercise and Nutrition Sciences, Deakin University, VIC 3125, Australia.
2	66P	Effect of mechanical stretching on Akt signalling and protein synthesis in myotubes — E.L. Brown, M.J. Quick, R.J. Snow and A.P. Russell, The Centre for Physical Activity and Nutrition Research (C-PAN), School of Exercise and Nutrition Sciences, Deakin University, VIC 3125, Australia.
3	67P	Are genuine changes in protein expression being overlooked? Avoiding pitfalls in Western blotting quantification using AMPK and calsequestrin 1 as the proteins of interest — J.P. Mollica,¹ J.S. Oakhill,² G.D. Lamb¹ and R.M. Murphy,¹ ¹Department of Zoology, La Trobe University, Melbourne, VIC 3086, Australia and ²St Vincent's Institute of Medical Research, Fitzroy, VIC 3065, Australia.
4	68P	Properties of Heat Shock Protein 25 and 72 in rat skeletal muscle — N.T. Larkins, R.M. Murphy and G.D. Lamb, Department of Zoology, La Trobe University, Melbourne, VIC 3086, Australia.
5	69P	Attenuation of glucose uptake is associated with reduced levels of striated activator of Rho signalling (STARS) in L6 myotubes — M.A. Wallace and A.P. Russell, The Centre for Physical Activity and Nutrition Research (C-PAN), School of Exercise and Nutrition Sciences, Deakin University, VIC 3215, Australia.
6	70P	The effect of estrogen on Akt signalling and protein synthesis in C2C12 mouse skeletal myotubes — R.J. Stefanetti, A.I. Turner, M.J. Quick, R.J. Snow and A.P. Russell, The Centre for Physical Activity and Nutrition Research (C-PAN), School of Exercise and Nutrition Sciences, Deakin University, VIC 3125, Australia.
7	71P	The relative amounts of PTEN protein in rat cardiac and skeletal muscles and the effect of high dose statins — C.A. Goodman, H. Yue, D.J. Pol and G.K. McConell, Department of Physiology, The University of Melbourne, Parkville, VIC 3010, Australia.
8	72P	Myostatin inhibition increases muscle mass in adult mdx dystrophic mice but does not enhance regenerative capacity of dystrophic skeletal muscle after injury — S.M. Snell, K.T. Murphy, R. Koopman and G.S. Lynch, Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, Victoria 3010, Australia.
9	73P	Macrophage polarization induced by different toll-like receptor agonists mediate insulin responses in muscle cells — J.D. Schertzer, V. Samokhvalov, P.J. Bilan, C.N. Antonescu and A. Klip, Cell Biology Program, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.
10	74P	Identifying the site of the source of reactive oxygen species within the mitochondria after transient exposure of cardiac myocytes to hydrogen peroxide — H.M. Viola,¹ E. Ingley,² P.G. Arthur¹ and L.C. Hool,¹ ¹School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Crawley, WA 6009, Australia and ²Western Australian Institute for Medical Research, Perth, WA 6000, Australia.
11	75P	Comparison of the cardiac-specific effects of dietary omega-3 and omega-6 polyunsaturated fatty acids in male and female rats — A.P. McAlindon, J.R. Bell, C.L. Curl, C.E. Huggins and L.M.D. Delbridge, Cardiac Phenomics Laboratory, Department of Physiology, The University of Melbourne, VIC 3010, Australia.
12	76P	Role of β-adrenoceptors during early skeletal muscle regeneration in mice — R. Sheorey, J.G. Ryall, J.E. Church and G.S. Lynch, Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, VIC 3010, Australia.
13	77P	Nitric oxide and skeletal muscle regeneration in mice after injury – the role of muscular nNOS — J.E. Church, S.M. Gehrig, G.K. McConell and G.S. Lynch, Basic & Clinical Myology Laboratory, Department of Physiology, University of Melbourne, VIC 3010, Australia.
14	78P	Developmental changes in contractile function of the diaphragm in the pre-term lamb — T. Lavin,¹ J. Pillow,² A.J. Bakker,¹ C. McLean² and G.J. Pinniger,¹ ¹School of Biomedical, Biomolecular and Chemical sciences, and ²School of Women and Infants Health, University of Western Australia, WA 6009, Australia.
15	79P	Regulation of atrogin-1 and protein degradation following incubation with dexamethasone and TNFα in mouse C2C12 and primary human myotubes — A.E. Larsen, T.C. Crowe and A.P. Russell, The Centre for Physical Activity and Nutrition Research (C-PAN), School of Exercise and Nutrition Sciences, Deakin University, VIC 3125, Australia.
16	80P	Store-dependent Ca²⁺ influx in intact healthy and dystrophic skeletal muscle — T.R. Cully,¹ O. Friedrich,¹ J.N. Edwards,^1,2 R.M. Murphy² and B.S. Launikonis,¹ ¹School of Biomedical Sciences, University of Queensland, St Lucia, QLD 4072, Australia and ²Department of Zoology, La Trobe University, Melbourne, VIC 3086, Australia.
17	81P	Evidence of impaired store-operated Ca²⁺ entry in aged mammalian skeletal muscle — J.N. Edwards,^1,2 O. Friedrich,¹ T.R. Cully,¹ R.M. Murphy² and B.S. Launikonis,¹ ¹School of Biomedical Sciences, University of Queensland, St Lucia, QLD 4072, Australia and ²Dept of Zoology, La Trobe University, Melbourne, VIC 3086, Australia.
18	82P	Examination of the expression of the cardiac muscle regulatory molecules, troponin T, I and C in the sheep heart across late gestation — G.S. Posterino,^1,3 S. Dunn,² K.J. Botting,^2,3 W. Wang,² H. Forbes² and J.L. Morrison,^2,3 ¹Department of Zoology, La Trobe University, Melbourne, VIC 8001, Australia Victoria3086, Australia, ²Early Origins of Adult Health Research Group, Sansom Institute, University of South Australia, Adelaide, SA 5001, Australia and ³Discipline of Physiology, University of Adelaide, Adelaide, SA 5005, Australia.
19	83P	Characterisation of Suppressor of Cytokine Signalling protein expression in regenerating mouse skeletal muscle after injury — J. Stratton, K.T. Murphy, C. van der Poel and G.S. Lynch, Basic & Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, VIC 3010, Australia.
20	84P	The effects of arsenic of the Na⁺/K⁺ ATPase transporter in the gills of the freshwater crayfish, Cherax destructor — Y. Lankadeva, G. Williams and J.M. West, School of Life and Environmental Sciences, Deakin University, 221 Burwood Hwy, Burwood, VIC 3125, Australia.
21	85P	Characterization of the muscle fibres types in a pristine and regenerate chela from the Christmas Island Red Crab Geocarcoidea natalis — J. Van Gramberg, S. Linton and J.M. West, School of Life and Environmental Sciences, Deakin University, 221 Burwood Hwy Burwood Victoria 3125, Australia.
22	86P	Comparison of contractile characteristics of permeabilized muscle fibres from the golden retriever muscular dystrophy (GRMD) dog and the mdx dystrophic mouse — H.Q. Lim,¹ C. van der Poel,¹ J.E. Church,¹ J.C.S. Bizario,² M.C.R. Costa,² M.L. Pinto² and G.S. Lynch,¹ ¹Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, VIC 3010, Australia and ²Associação de Amigos dos Portadores de Distrofia Muscular, University of Ribeirão Preto, São Paulo, Brasil.
23	87P	The location of nascent proteins in mechanically skinned skeletal muscle fibres of the rat — D.W. Jame,¹ M. Jois,² M. McDonagh³ and D.G. Stephenson,¹ ¹Department of Zoology, La Trobe University, VIC 3086, Australia, ²School of Life Sciences, La Trobe University, VIC 3086, Australia and ³Victorian Department of Primary Industries, Attwood, VIC 3049, Australia.
24	88P	The effect of taurine supplementation on taurine transporter content and ROS-induced lipid peroxidation during fatiguing contractions in rat skeletal muscle — C.A. Goodman,^1,2,4 D. Horvath,^3,4 C.G. Stathis,^3,4 K. Croft⁵ and A. Hayes,^3,4 ¹School of Human Movement, Recreation and Performance, Victoria University, Melbourne, VIC 8001, Australia., ²Department of Physiology, The University of Melbourne, Parkville, VIC 3010, Australia, ³School of Biomedical and Health Sciences, Victoria University, Melbourne, VIC 8001, Australia, ⁴Centre for Ageing, Rehabilitation, Exercise and Sport, Victoria University, Melbourne, VIC 8001, Australia and ⁵School of Medicine and Pharmacology, University of Western Australia, Crawley, WA 6009, Australia.
25	89P	Stretch-induced force enhancement in fast and slow skeletal muscle: implications for damage and disease — K.A. Ramsey, G.J. Pinniger and A.J. Bakker, Discipline of Physiology, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Crawley, WA 6009, Australia.
26	90P	Age-related alterations in transforming growth factor-β (TGF-β) signalling in rat skeletal muscle: implications for sarcopenia — K.T. Murphy, J.G. Ryall, R. Koopman and G.S. Lynch, Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, VIC 3010, Australia.
27	91P	Twitch kinetics of adult and aged EDL muscle from an α-actinin-3 knockout mouse — S. Chan,¹ S.I. Head¹ and K.N. North,² ¹Department of Physiology, University of New South Wales, NSW 2052, Australia and ²Children's Hospital at Westmead, Neurogenetics Research Unit, Westmead, NSW 2145, Australia.
28	92P	The effects of acute exercise and creatine supplementation on Akt signalling in human skeletal muscle — R.J. Snow, C.R. Wright, M.J. Quick, A.P. Garnham, K.K. Watt and A.P. Russell, The Centre for Physical Activity and Nutrition Research (C-PAN), School of Exercise and Nutrition Sciences, Deakin University, VIC 3125, Australia.
29	93P	Effects of exercise training and antioxidant supplementation on endothelial cell gene expression — A. Matsumoto,¹ L.C. Ward,² P.A. Wilce,² S.A. Marsh,³ R.G. Fassett⁴ and J.S. Coombes,¹ ¹School of Human Movement Studies, The University of Queensland, St Lucia QLD 4072, Australia, ²School of Molecular & Microbial Science, The University of Queensland, St Lucia QLD 4072, Australia, ³Department of Nutrition and Exercise Metabolism, Washington State University, PO Box 1495 Spokane WA 99210-1495, USA and ⁴Royal Brisbane Women's Hospital, GPO Box 48, Brisbane QLD 4001, Australia.
30	94P	The effect of acute exercise on skeletal muscle SIRT1 — S.E. Heywood, G.D. Wadley and G.K. McConell, Exercise Physiology and Metabolism Laboratory, Department of Physiology, The University of Melbourne, VIC 3010, Australia.
31	95P	Exercise-training increases skeletal muscle mitochondrial biogenesis despite inhibition of xanthine oxidase — M.A. Nicolas, G.K. McConell and G.D. Wadley, Department of Physiology, The University of Melbourne, Parkville, VIC 3010, Australia.
32	96P	No effect of statins or ezetimibe on fat metabolism during aerobic exercise in dyslipidaemic individuals — M.A. Matuszek¹ and R. Grant,^1,2 ¹School of Medical Sciences, University of New South Wales, NSW 2052, Australia and ²Australasian Research Institute, Sydney Adventist Hospital, Wahroonga, NSW 2076, Australia.
33	97P	Hyperaemic responses to forearm exercise — T. Van der Touw and M. Cook, School of Science and Technology, University of New England, Armidale, NSW 2351, Australia. (Introduced by Dr Gudrun Dieberg)
34	98P	The response of isolated tunica dartos muscle to acute and prolonged cold stimulation and noradrenaline — I. Nanayakkara, S.K. Maloney and A.J. Bakker, Discipline of Physiology, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, WA 6009, Australia.
35	99P	Uterine spontaneous contractions in the estrous cycle and the effect of mitochondrial inhibitors — F.S. Gravina,¹ K.P. Kerr,¹ S. Sandow,² R.B. de Oliveira,¹ H.C. Parkington,³ M.S. Imtiaz¹ and D.F. van Helden,¹ ¹School of Biomedical Sciences, University of Newcastle, NSW 2308, Australia, ²Department of Pharmacology, University of New South Wales, NSW 2052, Australia and ³Department of Physiology, Monash University, VIC 3800, Australia.
36	100P	The pacemaker and pattern generator underlying colonic migrating motor complexes does not require release of serotonin from the mucosa — D.J. Keating and N.J. Spencer, Department of Human Physiology, School of Medicine, Flinders University, SA 5001, Australia.
37	101P	Spatial relationships influence stimulus-secretion coupling in secretory epithelial cells — J. Low and P. Thorn, School of Biomedical Science, University of Queensland, QLD 4072, Australia.
38	102P	EGF and neurotensin mediated proliferation in HT-29 colon cancer cells; defining a role for the scaffold protein NHERF-1 — W.A. Kruger,¹ Y. Jang,¹ G.R. Monteith² and P. Poronnik,¹ ¹School of Biomedical Science, University of Queensland, St Lucia, Qld 2072, Australia and ²School of Pharmacy, University of Queensland, St Lucia, Qld 4072, Australia.
39	103P	Megalin binds to NHERF1 and NHERF2 scaffold proteins — K.A. Jenkin,¹ C. Slattery,² P. Poronnik² and D.H. Hryciw,¹ ¹School of Biomedical and Health Sciences, St Albans, Victoria University, VIC 8001, Australia and ² School of Biomedical Sciences, The University of Queensland, St Lucia, QLD 4069, Australia.
40	104P	Identification of glutamate transporter glast splice variants in hypoxic neonatal pig brain — A. Lee,¹ S. O'Driscoll,² D. Pow² and P. Poronnik,¹ ¹School of Biomedical Science, University of Queensland, Brisbane, Qld 4072, Australia and ²Centre for Clinical Research, University of Queensland, Royal Brisbane and Womens Hospital, Qld 4029, Australia.
41	105P	Protons released as a by-product of exocytosis affect the intracellular calcium response — N. Behrendorff and P. Thorn, School of Biomedical Sciences, University of Queensland, St Lucia, QLD 4072, Australia.
42	106P	Epithelial Sodium channels are regulated by the tyrosine kinase, c-Abl — S.H. Song, I.H. Lee, A. Dinudom and D.I. Cook, Discipline of Physiology, School of Medical Science, Faculty of Medicine, University of Sydney, Sydney, New South Wales 2006, Australia..
43	107P	Regulation of the rat glutamine transporter SNAT3 — S. Balkrishna, A. Bröer, A. Kingsland and S. Bröer, School of Biochemistry and Molecular Biology, The Australian National University, Canberra, ACT 0200, Australia.
44	108P	Distribution of the amino acid transporters B⁰AT1, B⁰AT2 and ASCT2 in kidney and intestine — N. Tietze,¹ J.M. Vanslambrouck,² J.E.J. Rasko² and S. Bröer,¹ ¹School of Biochemistry and Molecular Biology, The Australian National University, Canberra, ACT 0200, Australia and ²Gene and Stem Cell Therapy Program, Centenary Institute of Cancer Medicine and Cell Biology, University of Sydney, NSW 2050, Australia.
45	109P	Human sarcopenia reveals an increase in SOCS-3 and myostatin and a reduced efficiency of Akt phosphorylation — B. Léger,¹ W. Derave,² K. De Bock,³ P. Hespel² and A.P. Russell,⁴ ¹Institut de recherche en réadaptation-réinsertion, Avenue de Grandchampsec 90, Sion 1951, Switzerland, ²Research Centre for Exercise and Health, Faculty of Kinesiology and Rehabilitation Sciences, K.U.Leuven, B-3001, Belgium, ³Department of Movement and Sport Sciences, Ghent University, Ghent, Belgium and ⁴The Centre for Physical Activity and Nutrition Research (C-PAN), School of Exercise and Nutrition Sciences, Deakin University, VIC 3125, Australia.
46	110P	Contribution of Nitric Oxide to vagal nerve function in the dystrophin deficient heart — M. Watson, E. Lee and A. Hoey, Centre for Systems Biology, University of Southern Queensland, QLD, Australia.
47	111P	Phase resolved retardation measurements of isolated cardiomyocytes — N.M. Dragomir,¹ C.L. Curl,² A. Roberts¹ and L.M.D. Delbridge,² ¹School of Physics, University of Melbourne, Vic 3010, Australia and ²Department of Physiology, University of Melbourne, Vic 3010, Australia.
48	112P	An optimized RNA extraction protocol for stored human myocardial tissue biopsies — W.T.K. Ip,¹ C.E. Huggins,² S. Pepe³ and L.M.D. Delbridge,¹ ¹Cardiac Phenomics Laboratory, Department of Physiology, University of Melbourne, Parkville, VIC 3010, Australia, ²School of Exercise & Nutrition Sciences, Deakin University, Burwood, VIC 3125, Australia and ³Murdoch Children's Research Institute, Department of Cardiology, Royal Children's Hospital, Parkville, VIC 3010, Australia.
49	113P	Concentration dependent modulation of the cardiac ryanodine receptor by Homer1 — P. Pouliquin, S.M. Pace and A.F. Dulhunty, Division of Molecular Bioscience, JCSMR, ANU, Canberra, ACT 2601, Australia.
50	114P	F157A and Y160A substitutions in the helix 6 Region of GSTM2-2 C terminus reduces the inhibitory action of helix 6 on RyR2 channels — R. Hewawasam, D. Liu, M.G. Casarotto, P.G. Board and A.F. Dulhunty, Division of Molecular Bioscience, The John Curtin School of Medical Research, Australian National University, ACT 2601, Australia.
51	115P	Biophysical investigations of the cyclised skeletal muscle dihydropyridine receptor II-III loop — H-S. Tae, P.G. Board, M.G. Casarotto and A. F. Dulhunty, Division of Molecular Bioscience, The John Curtin School of Medical Research, The Australian National University, ACT 2601, Australia.
52	116P	Store independent activation and properties of Orai3/STIM1 mediated current — N.R. Scrimgeour and G.Y. Rychkov, Department of Physiology, University of Adelaide, Adelaide, 5005, Australia.
53	117P	Selective and voltage dependent inhibition of N-type calcium channels by novel ω-Conotoxins CVIE and CVIF — G. Berecki,^1,2 L. Motin,^1,2 A. Haythornthwaite,² N.L. Daly,³ P. Bansal,³ S. Vink,³ R. Drinkwater,⁴ R.J. Lewis,^3,4 P.F. Alewood³ and D.J. Adams,^1,2 ¹The Queensland Brain Institute, The University of Queensland, QLD 4072, Australia, ²The School of Biomedical Sciences, The University of Queensland, QLD 4072, Australia, ³The Institute for Molecular Biosciences, The University of Queensland, QLD 4072, Australia and ⁴Xenome Ltd, Indooroopilly, QLD 4069, Australia.
54	118P	Influence of mitochondria in the interspike interval pacemaking currents of mice Locus Coeruleus neurons — R.B. de Oliveira, M. Howlett, F.S. Gravina, M.S. Imtiaz, R.J. Callister, A.M. Brichta and D.F. van Helden, School of Biomedical Sciences, University of Newcastle, NSW 2308, Australia.
55	119P	Adiponectin causes insulin secretion with increased cytoplasmic calcium and inhibition of AMP Kinase in MIN6 cells — J.R. Rao,^1,2 H.C. Parkington,² D.J. Keating¹ and C. Chen,^1,2 ¹Prince Henry's Institute of Medical Research, Clayton, VIC 3168, Australia and ²Department of Physiology, Monash University, VIC 3800, Australia.
1530		Formal session ends

King Theatre

Chair: Stewart Head

Free communications: Muscle

1545	120P	Ageing alters the inflammatory response in rat skeletal muscles after injury — C. van der Poel,¹ J.G. Ryall,¹ J.D. Schertzer,¹ L.E. Gosselin² and G.S. Lynch,¹ ¹Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, VIC 3010, Australia and ²Department of Exercise and Nutrition Sciences, University at Buffalo, Buffalo, NY 14214, USA.
1600	121P	Influence of caveolin-3 upon membrane raft lipids and its implications for trafficking in muscle — O.L. Gervásio, W.D. Phillips and D.G. Allen, Bosch Institute, School of Medical Sciences, Anderson Stuart Building (F13), University of Sydney, NSW 2006, Australia.
1615	122P	Myoplasmic and sarcoplasmic reticulum calcium in intact mouse muscle during fatigue — D.G. Allen,² Y. Petersen,¹ I. Röder¹ and R. Rudolf,¹ ¹Institute for Toxicology & Genetics, Forschungszentrum Karsruhe and KIT, 76021 Karlsruhe, Germany and ²School of Medical Sciences and Bosch Institute, University of Sydney, NSW 2006, Australia.
1630	123P	Effect of S-nitrosoglutathione (GSNO) on excitation-contraction coupling in mechanically-skinned muscle fibres of the rat — T.L. Dutka, G.S. Posterino and G.D. Lamb, Department of Zoology, La Trobe University, Victoria 3086, Australia.
1645		Close

Wright Theatre

AuPS Invited Lecture &mdash Graham Lamb

Chair: David Adams

1700

124P

Exciting muscles: ion channels and excitation-contraction coupling in exercise and disease — G.D. Lamb, Department of Zoology, La Trobe University, Bundoora, Melbourne, VIC 3086, Australia.

1830 for 1900 Conference Dinner - University House

Wednesday 3 December 2008

King Theatre

Symposium: Epithelial Cell Biology

Chair: Stefan Bröer and Phil Poronnik

0830	125P	Diabetes and ACE2; light on the dark side of the renin angiotensin system — M.C. Thomas, Baker IDI Heart and Diabetes Institute, PO Box 6492, St Kilda Rd Central, Melbourne, VIC 8008, Australia. (Introduced by Stefan Bröer)
0850	126P	A GFP-based complementation screen for protein:protein interactions for the angiotensin type 1 receptor — W.G. Thomas, School of Biomedical Sciences, The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia.
0910	127P	Extracellular pH shifts and their consequences for secretory epithelial cells — P. Thorn and N. Behrendorff, School of Biomedical Science, University of Queensland, QLD 4072, Australia.
0930	128P	Purinergic regulation of epithelial Na⁺ channels — A. Dinudom, L.M. O'Mullane, C.R. Campbell and D.I. Cook, Discipline of Physiology and Bosch Institute, Faculty of Medicine, University of Sydney, NSW 2006, Australia.
0950	129P	An insight into epithelial cells through rare disorders — S. Bröer, School of Biochemistry & Molecular Biology, College of Medicine, Biology and Environment, Australian National University, Canberra, ACT 0200, Australia.
1010	130P	Insights into renal albumin handling — P. Poronnik, School of Biomedical Sciences, The University of Queensland, St Lucia, QLD 4072, Australia.
1030		Close

Wright Theatre

Symposium: Role of ROS in Cardiovascular Function and Disease

Chair: Livia Hool and David Allen

0830	131P	NADPH oxidase: role in muscular dystrophy — N.P. Whitehead and D.G. Allen, Discipline of Physiology, Bosch Institute, University of Sydney, NSW 2006, Australia.
0900	132P	NADPH oxidases in vascular biology and disease — C.P. Judkins,¹ H. Diep,¹ B.R.S. Broughton,¹ A.E. Mast,¹ G.J. Dusting,² C.G. Sobey¹ and G.R. Drummond,¹ ¹Department of Pharmacology, Monash University, Clayton, VIC 3800, Australia and ²Bernard O'Brien Institute of Microsurgery, Fitzroy, VIC 3065, Australia. (Introduced by David Allen)
0930	133P	Crosstalk between the L-type Ca²⁺ channel and the mitochondria — L.C. Hool, H.M. Viola and P.G. Arthur, Cardiovascular Electrophysiology Laboratory, School of Biomedical Biomolecular and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia.
1000	134P	Reactive oxygen species (ROS) and insulin resistant hypertrophic cardiomyopathy — L.M.D. Delbridge, Department of Physiology, University of Melbourne, VIC 3010, Australia.
1030		Close

1030-1100 Morning Tea - Alan Gilbert Building

King Theatre

Free communications: Membrane transport

Chair: Dan Markovich

1100	135P	A novel digestive complex and its role in Hartnup disorder: trafficking of the neutral amino acid transporter B⁰AT1 by angiotensin converting enzyme 2 (ACE2) — S. Kowalczuk,¹ A. Bröer,¹ N. Tietze,¹ J.M. Vanslambrouck,² J.E.J. Rasko^2,3 and S. Bröer,¹ ¹School of Biochemistry and Molecular Biology, Australian National University, Canberra, ACT 0200, Australia, ²Gene and Stem Cell Therapy Program, Centenary Institute of Cancer Medicine and Cell Biology, University of Sydney, Camperdown, NSW 2050, Australia and ³Cell and Molecular Therapies, Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia.
1115	136P	Regulation of epithelial sodium channels by G_αq — I.H. Lee, A. Dinudom, S. Kumar and D.I. Cook, Discipline of Physiology, School of Medical Science, University of Sydney, NSW 2006, Australia.
1130	137P	The epithelial sodium channel and blood pressure — C.J. Büsst, K.J. Scurrah, J.A. Ellis and S.B. Harrap, Department of Physiology, The University of Melbourne, VIC 3010, Australia.
1200	138P	Huntingtin-Associated Protein 1 (HAP-1) is a novel regulator of exocytosis — D.J. Keating,¹ L. Phillips,¹ X.F. Zhou² and K. Mackenzie,¹ ¹Molecular and Cellular Neuroscience Group, Department of Human Physiology and Centre for Neuroscience, Flinders University, Adelaide, Australia, 5042 and ²Neuroregeneration Laboratory, Department of Human Physiology and Centre for Neuroscience, Flinders University, Adelaide, Australia, 5042.
1215	139P	RCAN1 (Regulator of Calcineurin 1) is a novel regulator of secretory vesicle exocytosis and fusion pore kinetics — M.P. Zanin,¹ M. Pritchard² and D.J. Keating,^1,3 ¹Molecular and Cellular Neuroscience Group, Department of Human Physiology and Center for Neuroscience, Flinders University, Adelaide, SA 5042, Australia, ²Centre for Functional Genomics and Human Disease, Monash Institute of Medical Research, Monash University, Clayton, VIC 3168, Australia and ³Prince Henry’s Institute of Medical Research, Clayton, VIC 3168, Australia.
1230		Close

Wright Theatre

Symposium: Cardiac Growth and Ageing

Chair: Lea Delbridge and John Headrick

1100	140P	Age-associated changes in cardiac excitation-contraction coupling in ventricular myocytes isolated from male and female Fischer 344 rats — S.E. Howlett, Dalhousie University, Department of Pharmacology, 5850 College Street, Halifax, Nova Scotia, Canada B3H 1X5. (Introduced by Lea Delbridge)
1130	141P	Cardioprotective signalling in aging myocardium: failure of receptor-triggered protection — J.P. Headrick, J.N. Peart and K.J. Ashton, Heart Foundation Research Centre, Griffith University, Gold Coast, QLD 4217, Australia. (Introduced by Lea Delbridge)
1200	142P	Phosphoinositide 3-kinase (PI3K, p110α) and adaptive growth in the heart — J.R. McMullen, Cardiac Hypertrophy, Baker IDI Heart & Diabetes Institute, Melbourne, VIC 8008, Australia. (Introduced by L. M. Delbridge)
1230	143P	Metabolic challenges for cardiac mitochondria: from womb to tomb — S. Pepe, Murdoch Children’s Research Institute, Department of Cardiology, Royal Children's Hospital, Flemington Rd., Melbourne, VIC 3052, Australia. (Introduced by Lea M.D. Delbridge)
1300		Close

Gilbert Building

AuPS AGM (& lunch)

1300

Start

Wright Theatre

The Physiological Society (UK) Exchange Lecture - Colin Sibley

Chair: Joe Lynch

1430	144P	Fetal growth and placental physiology: From cell to community — C.P. Sibley, Maternal and Fetal Health Research Group, University of Manchester, St. Mary's Hospital, Manchester, M13 0JH, UK.
1530		Close

Wright Theatre

Prizes

1530		Presentations
1600		Close

1600 End of conference