AuPS Melbourne 2008 Meeting

Block Programme

This programme gives an overview of the meeting. The links take you to the detailed programme below.

Detailed Programme

In the programme below, each presentation has, beside the presentation time or poster board, the page number in volume 39 of the Proceedings. These numbers are links to the HTML versions of the pages. Each HTML page has a link to a corresponding PDF print version.

A PDF file of the abstracts for each platform and poster session can be accessed by clicking on the PDF symbol in the upper right of the programme block.

Links to the abstracts can also be found in the full author index and in the presenting author index.

Posters will be available for viewing througout the meeting. Presenting authors will be at their poster duing the poster session on Tuesday. Odd numbered posters will be manned from 1330-1430; even numbered ones from 1430-1530.

Sunday 30 November 2008

Wright Theatre

Plenary Lecture &mdash Lars Larsson

Chair: Gordon Lynch

1700 1P Regulation of human muscle contraction in health and disease — L. Larsson, Department of Clinical Neurophysiology, Uppsala University, Sweden, and Center for Development and Health Genetics, Penn State University, Pennsylvania, USA.
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1800-2000 Welcome reception - Alan Gilbert Building, Executive Lounge

Monday 1 December 2008

King Theatre

Symposium: Signaling in Cell Secretion

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Chair: Chen Chen and Peter Thorn

0830 2P Complex interactions between ghrelin and obestatin in the regulation of GH secretion and food intake — J. Epelbaum, UMR 894 Inserm, Faculté de Médecine, Université Paris Descartes, Centre de Psychiatrie et Neuroscience, 2 ter rue d’Alésia, 725014 Paris, France. (Introduced by C. Chen)
0900 3P The behaviour and control of post exocytic vesicles — P. Thorn and P. Bhat, School of Biomedical Sciences, The University of Queensland, QLD 4072, Australia.
0930 4P Integrating studies of proteins and lipids: dissecting the mechanism of Ca2+-triggered membrane fusion — J.R. Coorssen, Molecular Physiology, School of Medicine, University of Western Sydney, Campbelltown Campus, NSW 2570, Australia. (Introduced by C. Chen)
1000 5P Receptor- and metabolite-mediated increase in [Ca2+]i in rat pancreatic islet cells by free fatty acids — C. Chen and Y. Zhao, School of Biomedical Sciences, University of Queensland, Brisbane, QLD 4072, Australia.
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Wright Theatre

Symposium: Myopathies and Muscle Regeneration

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Chair: Gordon Lynch

0830 6P Using gene transfer technology to study muscle diseases — P. Gregorevic, Laboratory for Muscle Research & Therapeutics Development, Baker IDI Heart and Diabetes Institute, Melbourne, VIC 3004, Australia.
0900 7P Muscle hypertrophy and IGF-1 isoforms: is bigger better? — T. Shavlakadze,1 R. Chai,1 G.J. Pinniger,1 K. Maley,1 G. Grounds,1 N. Winn,2 N. Rosenthal2 and M.D. Grounds,1 1School of Anatomy and Human Biology, University of Western Australia, WA 6009, Australia and 2Mouse Biology Unit, EMBL Monterotondo Outstation, via Ramarini 32, 00016, Monterotondo, Rome, Italy.
0930 8P Novel regeneration in nemaline myopathy — A.J. Kee,1,2 J. Joya,1 V. Nair-Shalliker,1 M.A. Nguyen1 and E.H. Hardeman,3 1Muscle Development Unit, Children’s Medical Research Institute, Westmead, NSW 2145, Australia, 2Faculty of Medicine, University of Sydney, NSW 2006, Australia and 3Department of Anatomy, School of Medical Science, University of New South Wales, Kensington, NSW 2052, Australia.
1000 9P Acute Quadriplegic Myopathy and myosin loss in ICU patients: Underlying mechanisms, improved diagnostics and a specific intervention strategy — L. Larsson,1,3 J. Ochala,1 V. Banduseela,1 A-M. Gustafsson,1 P. Radell,2 L.I. Eriksson2 and B. Dworkin,1 1Department of Clinical Neurophysiology, Uppsala University, Sweden, 2Dept of Anaesthesia and Intensive Care, Karolinska Institute, Sweden and 3Department of Neuroscience and Center for Development and Health Genetics, Penn State University, Pennsylvania, U.S.A. (Introduced by G.S. Lynch)
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Morning Tea - Alan Gilbert Building

King Theatre

Symposium: Regulation of Trafficking of Membrane Transporters by Intracellular Signaling Systems

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Chair: David Cook

1100 10P New insights into the formation and function of caveolae — R.G. Parton, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland 4072, Australia. (Introduced by D.I. Cook)
1130 11P Regulation of receptors, transporters and ion channels by the Nedd4 family of ubiquitin ligases — S. Kumar,1,6 N. Boase,1 B. Yang,2 R. Daly,3 S. Townley,1 A. Dinudom,4 D.I. Cook,4 P. Poronnik5 and G.Y. Rychkov,6 1Hanson Institute, IMVS, SA 5000, Australia, 2Department of Obsterics and Gynecology, University of Iowa, IA 52242, USA, 3Garvan Institute, Sydney, NSW 2010, Australia, 4Dicipline of Physiology, Faculty of Medicine, University of Sydney, NSW 2006, Australia, 5School of Biomedical Sciences, University of Queensland, QL 4067, Australia and 6Discipline of Physiology, School of Molecular and Biomedical Sciences, University of Adelaide, SA 5005, Australia.
1200 12P The role of phospholipids in controlling GLUT4 exocytosis — W.E. Hughes, Garvan Institute, 384 Victoria Street, Darlinghurst, NSW 2010, Australia. (Introduced by Anuwat Dinudom)
1230 13P The physiological roles of sulfate transporters — D. Markovich, School of Biomedical Sciences, University of Queensland, St. Lucia, QLD 4072, Australia.
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Wright Theatre

Free communications: Muscle

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Chair: Anthony Bakker

1100 14P The effects of arsenic on the two major fibre types in the chelae of the freshwater crayfish Cherax destructor (Clarke) — G. Williams and J.M. West, School of Life and Environmental Sciences, Deakin University, 221 Burwood Hwy, Burwood, VIC 3125, Australia.
1115 15P Development of the diaphragm and the effects of maternal creatine supplementation on birth hypoxia in a novel precocial species, the spiny mouse (Acomys cahirinus) — D. Cannata,1 Z. Ireland,2 H. Dickinson,3 D.W. Walker2 and J.M. West,1 1School of Life and Environmental Sciences, Deakin University, 221 Burwood Hwy, Burwood,VIC 3125, Australia, 2Department of Physiology, Monash University, Clayton, VIC 3168, Australia and 3Monash Immunology & Stem Cell Laboratories, Monash University, Clayton, VIC 3168, Australia.
1130 16P Unique actions of junctin and triadin on skeletal muscle ryanodine receptor calcium release channels — L. Wei, A.F. Dulhunty and N.A. Beard, Muscle Research Group, The John Curtain School of Medical Research, The Australian National University, Canberra, ACT 0200, Australia..
1145 17P The force-generating attachment of myosin heads (cross-bridges) to the actin filaments is controlled differently in fast- and slow-muscle fibre types — D.G. Stephenson,1 O. Andruchov,2 G.M.M. Stephenson3 and S. Galler,2 1Department of Zoology, La Trobe University, Vic 3086, Australia, 2Department of Cell Biology, University of Salzburg, A-5020, Austria and 3Muscle Cell Biochemistry Laboratory, School of Biomedical and Health Sciences Victoria University, VIC 8001, Australia.
1200 18P Conformational coupling of store-operated Ca2+ entry in skeletal muscle — B.S. Launikonis, J.N. Edwards, F. von Wegner and O. Friedrich, School of Biomedical Sciences, University of Queensland, St Lucia, Qld 4072, Australia.
1215 19P Store-operated Ca2+ entry in dystrophic skeletal muscle is not a source for Ca2+ overload due to robust deactivation — O. Friedrich,1 J.N. Edwards,1 R.M. Murphy2 and B.S. Launikonis,1 1University of Queensland, School of Biomedical Sciences, St Lucia campus, Brisbane, QLD 4072, Australia and 2La Trobe University, Bundoora campus, Department of Zoology, Melbourne, VIC 3086, Australia.
1230 20P Calcium transients in fast-twitch FDB skeletal muscle from old dystrophic mice — S.I. Head, Department of Physiology, University of New South Wales, Sydney, NSW 2052, Australia.
1245 21P Blocking TNF (using cV1q) reduces the severity of stretch-induced muscle damage in dystrophic, mdx mice — A.T. Piers,1,2 A.J. Bakker,1 H.G. Radley,2 M.D. Grounds2 and G.J. Pinniger,1 1School of Biomedical, Biomolecular and Chemical Sciences, University of Western Austalia, WA 6009, Australia and 2School of Anatomy and Human Biology, University of Western Austalia, WA 6009, Australia.
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1300-1400 Lunch

King Theatre

Free communications: Ion Channels

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Chair: Alan Bretag

1400 22P Effect of volatile anaesthetics on the calcium release channel in the heart — D.R. Laver, T. Quail, H. Sitsapesan and D.F. van Helden, School of Biomedical Sciences, University of Newcastle and Hunter Medical Research Institute, Callaghan, NSW 2308, Australia.
1415 23P The role of depolarising and repolarising currents in the induction of early afterdepolarisations during acute hypoxia in ventricular myocytes — W.A. Macdonald,1 N. Gaur,2 Y. Rudy2 and L.C. Hool,1 1School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, Crawley, WA 6009, Australia and 2Cardiac Bioelectricity and Arrhythmia Center, Washington University, St Louis, MO 63130-4899, USA.
1430 24P Ageing related change in store-operated Ca2+ influx and TRPCs expression of sinoatrial node — Y.K. Ju, D. Lai and D.G. Allen, School of Medical Sciences, Bosch institute, University of Sydney, NSW 2006, Australia.
1445 25P Delineating the gating pathway in the α1 glycine receptor ligand-binding domain — S.A. Pless and J.W. Lynch, Queensland Brain Institute and School of Biomedical Sciences, University of Queensland, Brisbane, QLD 4072, Australia..
1500 26P External divalent ions increase anion-cation permeability in glycine receptor channels – consideration of ion activities, surface charge and conductance measurements — P.H. Barry,1 S. Sugiharto,1 J.E. Carland,1 T.M. Lewis,1 P.R. Schofield2 and A.M. Moorhouse,1 1Department of Physiology and Pharmacology, School of Medical Sciences, University of New South Wales, NSW 2052, Australia and 2The Prince of Wales Medical Research Institute, Barker Street, Randwick, NSW 2031, Australia.
1515 27P FRET study of C-terminal movements of the cytoplasmic tail of human skeletal muscle chloride channel, hClC-1, during gating — L. Ma,1,2 G.Y. Rychkov,2 E.A. Bykova,3 J. Zheng3 and A.H. Bretag,1 1Sansom Institute, University of South Australia, North Terrace, Adelaide, SA 5000, Australia, 2Physiology Discipline, School of Molecular and Biomedical Science, University of Adelaide, SA 5005, Australia and 3Department of Physiology and Membrane Biology, University of California at Davis, Davis, CA 95616, USA.
1530 28P Neonatal hypoxia increases hippocampal excitability in adulthood: Gender differences and prevention by neurosteroid treatment — H.A. Coleman,1 C. Moller,1 T. Yawno,1 D.W. Walker,1 D.C. Reutens2 and H.C. Parkington,1 1Department of Physiology, Monash University, Clayton Vic 3800, Australia and 2Department of Medicine, Monash Medical Centre, Clayton Road, Clayton Vic 3168, Australia.
1545 29P A quantifiable approach to filtering and analysis of cellular fluorescence imaging — J.L. Bourke,1 H. Hashitani,2 H. Suzuki2 and R.J. Lang,1 1Department of Physiology, Monash University, Victoria 3800, Australia and 2Department of Regulatory Cell Physiology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan.
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Wright Theatre

Symposium: Skeletal Muscle: an Endocrine Organ

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Chair: Mark Febbraio

1400 30P PGC-1α in muscle links metabolism to inflammation — C. Handschin, University of Zurich, Institute of Physiology and Zurich Center for Integrative Human Physiology (ZIHP), Winterthurerstrasse 190, CH-8057 Zurich, Switzerland. (Introduced by Mark Febbraio)
1440 31P Role of protease-activated receptors (PARs) in muscle inflammation and cytokine release — A.J. Bakker, K.A. Burlinson, G.J. Pinniger, N. Asokananthan and G.A. Stewart, School of Biomedical, Biomolecular & Chemical Sciences, University of Western Australia, WA 6009, Australia.
1520 32P Myokines and metabolic regulation — M.A. Febbraio1 and B.K. Pedersen,2 1Cellular & Molecular Metabolism Laboratory, Division of Metabolism & Obesity, Baker IDI Heart & Diabetes Institute, 75 Commercial Rd, Melbourne, VIC 3004, Australia. and 2Centre of Inflammation and Metabolism, Rigshospitalet - Section 7641, Blegdamsvej 9, DK-2100, Copenhagen, Denmark.
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1600-1630 Afternoon Tea - Alan Gilbert Building

King Theatre

Free Communications: Cardiovascular/Kidney

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Chair: Livia Hool

1630 33P Cardiac hypertrophy and oxidative stress are associated with insulin resistance in fructose fed mice — K.M. Mellor,1 R.H. Ritchie2 and L.M.D. Delbridge,1 1Department of Physiology, University of Melbourne, VIC 3010, Australia and 2Heart Failure Pharmacology, Baker IDI Heart & Diabetes Institute, Melbourne, VIC 3004, Australia.
1645 34P Comparison of anoxic tolerance of isolated cardiac myocytes from male and female rats — I.R. Wendt,1,2 M. Vila Petroff,1,3 C.L. Curl,1 J.R. Bell,1 A. Mattiazzi3 and L.M.D. Delbridge,1 1Department of Physiology, The University of Melbourne, VIC 3010, Australia, 2Department of Physiology, Monash University, VIC 3080, Australia and 3Facultad de Ciencias Médicas, Centro de Investigaciones Cardiovasculares, UNLP, Argentina.
1700 35P The Hypertrophic Heart Rat (HHR) exhibits enhanced myocardial PI3-K mediated signalling in the neonate, but not in the adult — J.R. Bell, E.R. Porrello, S.B. Harrap and L.M.D. Delbridge, Department of Physiology, The University of Melbourne, VIC 3010, Australia.
1715 36P Mechanisms maintaining kidney tissue oxygenation during renal ischaemia in anaesthetised rabbits — R.G. Evans,1 S. Michaels,1 G.A. Eppel,1 S.L. Burke,2 G.A. Head,2 J.F. Carroll3 and P.M. O'Connor,4 1Department of Physiology, Monash University, Victoria 3800, Australia, 2Baker IDI Heart and Diabetes Institute, Melbourne, Victoria 8008, Australia, 3Department of Integrative Physiology, University of North Texas Health Science Center, Fort Worth, Texas 76107, USA and 4Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53202, USA.
1730 37P Computational modelling of oxygen transport in the whole kidney — B.S. Gardiner,1 R.G. Evans,2 P.M. O'Connor3 and D.W. Smith,1,4 1Department of Civil and Environmental Engineering, The University of Melbourne, Melbourne, VIC 3010, Australia, 2Department of Physiology, Monash University, Melbourne, VIC 3800, Australia, 3Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA and 4Faculty of Engineering, Computing and Mathematics, University of Western Australia, Perth, WA 6009, Australia.
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Wright Theatre

Free communications: Exercise

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Chair: Mike McKenna

1630 38P Can the increase in mitochondrial biogenesis in skeletal muscle following acute exercise be prevented by antioxidant supplementation? — G.D. Wadley, J. Bloom, A. Jamieson, J. Owen, D. Tait and G.K. McConell, Department of Physiology, The University of Melbourne, Parkville, VIC 3010, Australia.
1645 39P Aberrent skeletal muscle mitochondrial responses to exercise in overweight women with polycystic ovary syndrome (PCOS) — N.K. Stepto,1,2,3 D. Rachon,2,4 C. Harrison,2,3 S. Hutchison,2 B. Strauss,5 M. Cooper,6 R. Southgate,6 C. Bruce,6 M.A. Febbraio6 and H.J. Teede,2 1Centre for Ageing Rehabilitation Exercise and Sport, Victoria University, Melbourne, VIC 8001, Australia, 2Jean Hailes Foundation for Women’s Health Research Group, Centre for Womens Health, Monash Institute of Health Research, Clayton, VIC 3168, Australia, 3Department of Physiology, Monash University Clayton, VIC 3800, Australia, 4Department of Clinical Nutrition, Medical University of GdaÅ„sk, GdaÅ„sk, Poland, 5Clinical Nutrition & Metabolism, Monash Medical Centre Southern Health, Clayton, VIC 3800, Australia and 6Cellular and Molecular Metabolism Laboratory, Baker Research Institute, Melbourne, VIC 3181, Australia.
1700 40P Effects of antioxidant supplementation and exercise training on skeletal muscle antioxidant enzymes and mitochondrial biogenesis — N.A. Strobel,1 J.M. Peake,1 A. Matsumoto,1 S.A. Marsh,2 J.S. Coombes1 and G.D. Wadley,3 1School of Human Movement Studies, The University of Queensland, St Lucia, QLD 4072, Australia, 2Department of Nutrition and Exercise Metabolism, Washington State University, PO Box 1495, Spokane, WA 99210-1495, USA and 3Department of Physiology, The University of Melbourne, Parkville, VIC 3010, Australia.
1715 41P Nitric oxide and ROS regulate skeletal muscle glucose uptake during contraction independent of AMPK α2 — T.L. Merry,1 G.R. Steinberg,2 G.S. Lynch1 and G.K. McConell,1 1Department of Physiology, The University of Melbourne, VIC 3010, Australia and 2St. Vincent's Institute of Medical Research, Fitzroy, VIC 3065, Australia.
1730 42P Iron overload in skeletal muscle; redox stress and exercise capacity — T.F. Reardon and D.G. Allen, School of Medical Sciences (F13), Bosch Institute, The University of Sydney, NSW 2006, Australia.
1745 43P The effect of continuous vs intermittent exercise on substrate utilization during exercise and recovery in healthy adults — M.L. Borg, C.G. Stathis and A. Hayes, Exercise Metabolism Unit, School of Biomedical and Health Sciences, Victoria University, Footscray, Victoria 3011, Australia.
1800 Close

King Theatre

Student symposium: Beyond your PhD

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Chair: Stefan Gehrig

1800 44P Beyond your PhD: Key considerations in planning your post-doctoral career path — P. Gregorevic, Laboratory for Muscle Research & Therapeutics Development, BakerIDI Heart and Diabetes Institute Melbourne, VIC 3004, Australia.
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1930-late Student Mixer - Redback Brewery Hotel, 75 Flemington Road, North Melbourne

Tuesday 2 December 2008

King Theatre

Symposium: Signaling in Smooth Muscles

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Chair: James Brock and Dirk van Helden

0830 45P Ca2+ phase waves - a fundamental mechanism underlying propagation of gastric slow waves — D.F. van Helden, D.R. Laver and M.S. Imtiaz, School of Biomedical Sciences and Hunter Medical Research Institute, Faculty of Health, University of Newcastle, NSW 2308, Australia.
0900 46P Molecular and biophysical properties of smooth muscle-type voltage-gated Na+ channels — N. Teramoto, Department of Pharmacology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan. (Introduced by Dr James Brock)
0930 47P Spontaneous electrical and Ca2+ signals in the mouse renal pelvis that drive pyeloureteric peristalsis — R.J. Lang,1 H. Hashitani,2 M.A. Tonta,1 J.L. Bourke,1 H.C. Parkington1 and H. Suzuki,2 1Department of Physiology, School of Biomedical Sciences, Monash University, Clayton, Vic 3800, Australia and 2Department of Regulatory Cell Physiology, Nagoya City University Grad School, Nagoya 467-8601, Japan.
1000 48P Do K+ channels play a role in noradrenergic signalling in vascular smooth muscle? — J.A. Brock and N.M. Rummery, Prince of Wales Medical Research Institute, Sydney, NSW 2031, Australia..
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Wright Theatre

Symposium: Signals Mediating Exercise-Induced Skeletal Muscle Remodelling

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Chair: Mark Hargreaves

0830 49P Histone modifications and skeletal muscle metabolic gene expression — S.L. McGee, Department of Physiology, The University of Melbourne, VIC 3010, Australia.
0900 50P Molecular regulation of skeletal muscle mass — A.P. Russell, The Centre for Physical Activity and Nutrition Research (C-PAN), School of Exercise and Nutrition Sciences, Deakin University, VIC 3125, Australia.
0930 51P Calpains and skeletal muscle function — R.M. Murphy and G.D. Lamb, Department of Zoology, La Trobe University, Melbourne, VIC 3086, Australia.
1000 52P A novel role for β-adrenoceptor signalling in the regulation of skeletal muscle mass — J.G. Ryall and G.S. Lynch, Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, VIC 3010, Australia.
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1030-1100 Morning Tea - Alan Gilbert Building

King Theatre

Symposium: Ion Channels as Therapeutic Targets for Multiple Diseases

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Chair: David Adams

1100 53P Novel approaches for screening sodium channel function in drug discovery — S. Petrou, E.A. Thomas and B.B. Scaf, Howard Florey Institute, The University of Melbourne, VIC 3010, Australia.
1130 54P Translational promise and physiological insights in Aquaporin drug discovery — A.J. Yool, Discipline of Physiology, School of Molecular & Biomedical Science, University of Adelaide, Adelaide, SA 5005, Australia.
1200 55P The capsaicin receptor, TRPV1, as a target for chronic pain therapy — A. Bhaskaracharya,1 H-J. Cho,2 E. Jennings,2 J. Ziogas1 and P. McIntyre,1 1Department of Pharmacology, University of Melbourne and 2Department of Anatomy and Cell Biology, University of Melbourne, Melbourne, VIC 3010, Australia. (Introduced by David Adams)
1230 56P The P2X7 receptor and its genetic variants; relation to mood disorders — J.S. Wiley, L. Stokes, S.J. Fuller, R. Sluyter, K.K. Skarratt and B.J. Gu, Department of Medicine, University of Sydney, Nepean Hospital, Penrith, NSW 2750, Australia. (Introduced by David Adams)
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Wright Theatre

Free communications: Metabolism and Signalling

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Chair: Sean McGee

1100 57P The role of an endogenous regulator of calcineurin in the regulation of glucose homeostasis — H.S. Peiris and D.J. Keating, Molecular and Cellular Neuroscience Group, Department of Human Physiology and Center for Neuroscience, Flinders Univeristy, Adelaide, SA 5001, Australia.
1115 58P Acute stimulation of fatty acid oxidation does not alter energy expenditure — N. Turner, E. Preston, D. Wilks, M.M. Swarbrick, B.D. Hegarty, E.W. Kraegen and G.J. Cooney, Diabetes & Obesity Research Program, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia.
1130 59P Glucose and insulin modulate the expression and activity of the thioredoxin antioxidant system in cultured human skeletal muscle fibres — N. Stupka,1 S.D. Martin,1 J.M. McKenzie,1 F.M. Collier2 and N. Konstantopoulos,3 1Institute of Biotechnology, Deakin University, Waurn Ponds, VIC 3217, Australia, 2Barwon Biomedical Research, Barwon Health, Geelong, VIC 3220, Australia and 3Metabolic Research Unit, Deakin University, Waurn Ponds, VIC 3217, Australia.
1145 60P Role of nitric oxide in mitochondrial biogenesis in L6 myocytes — G.P.Y. Ng,1 M. Phillips,1 L. Macaulay,2 G.D. Wadley1 and G.K. McConell,1 1Department of Physiology, University of Melbourne, Parkville, VIC 3010, Australia and 2Obesity and Diabetes Treatment Laboratory, CSIRO, Parkville, VIC 3010, Australia.
1200 61P Effects of simvastatin on skeletal muscle mitochondrial biogenesis and mitochondrial enzyme activities — D.J. Pol,1 P.K. Kennedy,2 G.K. McConell1 and C.A. Goodman,1 1Department of Physiology, University of Melbourne, VIC 3010, Australia and 2State Neuropathology Service, Department of Pathology, University of Melbourne, VIC 3010, Australia.
1215 62P Ingestion of a protein hydrolysate is accompanied by an accelerated in vivo digestion and absorption rate when compared with its intact protein — R. Koopman,1,2 S. Walrand,3 A.K. Kies,4 W.H.M. Saris,1 Y. Boirie3 and L.J.C. van Loon,1 1Nutrition and Toxicology Research Institute Maastricht (NUTRIM), Maastricht University, Maastricht, The Netherlands, 2Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, VIC 3010, Australia, 3Université Clermont Auvergne, Centre de Recherche en Nutrition Humaine, Clermont-Ferrand Cedex 1, France and 4DSM Food Specialties, R&D, Biochemistry and Nutrition Department, Delft, The Netherlands.
1230 63P Local insulin-like growth factor binding proteins are essential for successful skeletal muscle regeneration — S.M. Gehrig, J.D. Schertzer, J.E. Church and G.S. Lynch, Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, VIC 3010, Australia.
1245 64P Human sarcopenia reveals an increase in SOCS-3 and myostatin and a reduced efficiency of Akt phosphorylation — B. Léger,1 W. Derave,2 K. De Bock,3 P. Hespel4 and A.P. Russell,5 1Clinique romande de réadaptation SuvaCare, Sion 1951, Switzerland, 2Institut de recherche en réadaptation-réinsertion, Sion 1951, Switzerland, 3Research Centre for Exercise and Health, Faculty of Kinesiology and Rehabilitation Sciences, K.U. Leuven, B-3001, Belgium, 4Department of Movement and Sport Sciences, Ghent University, Ghent, Belgium and 5The Centre for Physical Activity and Nutrition Research (C-PAN), School of Exercise and Nutrition Sciences, Deakin University, VIC 3125, Australia..
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Alan Gilbert Building

Lunch and Posters

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1300 Session opens
1 65P PGC-1α reduces proteasome and lysosome activity and attenuates myotube protein degradation — P. Sepulveda, M.J. Quick, M.A. Wallace, R.J. Snow and A.P. Russell, The Centre for Physical Activity and Nutrition Research (C-PAN), School of Exercise and Nutrition Sciences, Deakin University, VIC 3125, Australia.
2 66P Effect of mechanical stretching on Akt signalling and protein synthesis in myotubes — E.L. Brown, M.J. Quick, R.J. Snow and A.P. Russell, The Centre for Physical Activity and Nutrition Research (C-PAN), School of Exercise and Nutrition Sciences, Deakin University, VIC 3125, Australia.
3 67P Are genuine changes in protein expression being overlooked? Avoiding pitfalls in Western blotting quantification using AMPK and calsequestrin 1 as the proteins of interest — J.P. Mollica,1 J.S. Oakhill,2 G.D. Lamb1 and R.M. Murphy,1 1Department of Zoology, La Trobe University, Melbourne, VIC 3086, Australia and 2St Vincent's Institute of Medical Research, Fitzroy, VIC 3065, Australia.
4 68P Properties of Heat Shock Protein 25 and 72 in rat skeletal muscle — N.T. Larkins, R.M. Murphy and G.D. Lamb, Department of Zoology, La Trobe University, Melbourne, VIC 3086, Australia.
5 69P Attenuation of glucose uptake is associated with reduced levels of striated activator of Rho signalling (STARS) in L6 myotubes — M.A. Wallace and A.P. Russell, The Centre for Physical Activity and Nutrition Research (C-PAN), School of Exercise and Nutrition Sciences, Deakin University, VIC 3215, Australia.
6 70P The effect of estrogen on Akt signalling and protein synthesis in C2C12 mouse skeletal myotubes — R.J. Stefanetti, A.I. Turner, M.J. Quick, R.J. Snow and A.P. Russell, The Centre for Physical Activity and Nutrition Research (C-PAN), School of Exercise and Nutrition Sciences, Deakin University, VIC 3125, Australia.
7 71P The relative amounts of PTEN protein in rat cardiac and skeletal muscles and the effect of high dose statins — C.A. Goodman, H. Yue, D.J. Pol and G.K. McConell, Department of Physiology, The University of Melbourne, Parkville, VIC 3010, Australia.
8 72P Myostatin inhibition increases muscle mass in adult mdx dystrophic mice but does not enhance regenerative capacity of dystrophic skeletal muscle after injury — S.M. Snell, K.T. Murphy, R. Koopman and G.S. Lynch, Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, Victoria 3010, Australia.
9 73P Macrophage polarization induced by different toll-like receptor agonists mediate insulin responses in muscle cells — J.D. Schertzer, V. Samokhvalov, P.J. Bilan, C.N. Antonescu and A. Klip, Cell Biology Program, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.
10 74P Identifying the site of the source of reactive oxygen species within the mitochondria after transient exposure of cardiac myocytes to hydrogen peroxide — H.M. Viola,1 E. Ingley,2 P.G. Arthur1 and L.C. Hool,1 1School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Crawley, WA 6009, Australia and 2Western Australian Institute for Medical Research, Perth, WA 6000, Australia.
11 75P Comparison of the cardiac-specific effects of dietary omega-3 and omega-6 polyunsaturated fatty acids in male and female rats — A.P. McAlindon, J.R. Bell, C.L. Curl, C.E. Huggins and L.M.D. Delbridge, Cardiac Phenomics Laboratory, Department of Physiology, The University of Melbourne, VIC 3010, Australia.
12 76P Role of β-adrenoceptors during early skeletal muscle regeneration in mice — R. Sheorey, J.G. Ryall, J.E. Church and G.S. Lynch, Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, VIC 3010, Australia.
13 77P Nitric oxide and skeletal muscle regeneration in mice after injury – the role of muscular nNOS — J.E. Church, S.M. Gehrig, G.K. McConell and G.S. Lynch, Basic & Clinical Myology Laboratory, Department of Physiology, University of Melbourne, VIC 3010, Australia.
14 78P Developmental changes in contractile function of the diaphragm in the pre-term lamb — T. Lavin,1 J. Pillow,2 A.J. Bakker,1 C. McLean2 and G.J. Pinniger,1 1School of Biomedical, Biomolecular and Chemical sciences, and 2School of Women and Infants Health, University of Western Australia, WA 6009, Australia.
15 79P Regulation of atrogin-1 and protein degradation following incubation with dexamethasone and TNFα in mouse C2C12 and primary human myotubes — A.E. Larsen, T.C. Crowe and A.P. Russell, The Centre for Physical Activity and Nutrition Research (C-PAN), School of Exercise and Nutrition Sciences, Deakin University, VIC 3125, Australia.
16 80P Store-dependent Ca2+ influx in intact healthy and dystrophic skeletal muscle — T.R. Cully,1 O. Friedrich,1 J.N. Edwards,1,2 R.M. Murphy2 and B.S. Launikonis,1 1School of Biomedical Sciences, University of Queensland, St Lucia, QLD 4072, Australia and 2Department of Zoology, La Trobe University, Melbourne, VIC 3086, Australia.
17 81P Evidence of impaired store-operated Ca2+ entry in aged mammalian skeletal muscle — J.N. Edwards,1,2 O. Friedrich,1 T.R. Cully,1 R.M. Murphy2 and B.S. Launikonis,1 1School of Biomedical Sciences, University of Queensland, St Lucia, QLD 4072, Australia and 2Dept of Zoology, La Trobe University, Melbourne, VIC 3086, Australia.
18 82P Examination of the expression of the cardiac muscle regulatory molecules, troponin T, I and C in the sheep heart across late gestation — G.S. Posterino,1,3 S. Dunn,2 K.J. Botting,2,3 W. Wang,2 H. Forbes2 and J.L. Morrison,2,3 1Department of Zoology, La Trobe University, Melbourne, VIC 8001, Australia Victoria3086, Australia, 2Early Origins of Adult Health Research Group, Sansom Institute, University of South Australia, Adelaide, SA 5001, Australia and 3Discipline of Physiology, University of Adelaide, Adelaide, SA 5005, Australia.
19 83P Characterisation of Suppressor of Cytokine Signalling protein expression in regenerating mouse skeletal muscle after injury — J. Stratton, K.T. Murphy, C. van der Poel and G.S. Lynch, Basic & Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, VIC 3010, Australia.
20 84P The effects of arsenic of the Na+/K+ ATPase transporter in the gills of the freshwater crayfish, Cherax destructor — Y. Lankadeva, G. Williams and J.M. West, School of Life and Environmental Sciences, Deakin University, 221 Burwood Hwy, Burwood, VIC 3125, Australia.
21 85P Characterization of the muscle fibres types in a pristine and regenerate chela from the Christmas Island Red Crab Geocarcoidea natalis — J. Van Gramberg, S. Linton and J.M. West, School of Life and Environmental Sciences, Deakin University, 221 Burwood Hwy Burwood Victoria 3125, Australia.
22 86P Comparison of contractile characteristics of permeabilized muscle fibres from the golden retriever muscular dystrophy (GRMD) dog and the mdx dystrophic mouse — H.Q. Lim,1 C. van der Poel,1 J.E. Church,1 J.C.S. Bizario,2 M.C.R. Costa,2 M.L. Pinto2 and G.S. Lynch,1 1Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, VIC 3010, Australia and 2Associação de Amigos dos Portadores de Distrofia Muscular, University of Ribeirão Preto, São Paulo, Brasil.
23 87P The location of nascent proteins in mechanically skinned skeletal muscle fibres of the rat — D.W. Jame,1 M. Jois,2 M. McDonagh3 and D.G. Stephenson,1 1Department of Zoology, La Trobe University, VIC 3086, Australia, 2School of Life Sciences, La Trobe University, VIC 3086, Australia and 3Victorian Department of Primary Industries, Attwood, VIC 3049, Australia.
24 88P The effect of taurine supplementation on taurine transporter content and ROS-induced lipid peroxidation during fatiguing contractions in rat skeletal muscle — C.A. Goodman,1,2,4 D. Horvath,3,4 C.G. Stathis,3,4 K. Croft5 and A. Hayes,3,4 1School of Human Movement, Recreation and Performance, Victoria University, Melbourne, VIC 8001, Australia., 2Department of Physiology, The University of Melbourne, Parkville, VIC 3010, Australia, 3School of Biomedical and Health Sciences, Victoria University, Melbourne, VIC 8001, Australia, 4Centre for Ageing, Rehabilitation, Exercise and Sport, Victoria University, Melbourne, VIC 8001, Australia and 5School of Medicine and Pharmacology, University of Western Australia, Crawley, WA 6009, Australia.
25 89P Stretch-induced force enhancement in fast and slow skeletal muscle: implications for damage and disease — K.A. Ramsey, G.J. Pinniger and A.J. Bakker, Discipline of Physiology, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Crawley, WA 6009, Australia.
26 90P Age-related alterations in transforming growth factor-β (TGF-β) signalling in rat skeletal muscle: implications for sarcopenia — K.T. Murphy, J.G. Ryall, R. Koopman and G.S. Lynch, Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, VIC 3010, Australia.
27 91P Twitch kinetics of adult and aged EDL muscle from an α-actinin-3 knockout mouse — S. Chan,1 S.I. Head1 and K.N. North,2 1Department of Physiology, University of New South Wales, NSW 2052, Australia and 2Children's Hospital at Westmead, Neurogenetics Research Unit, Westmead, NSW 2145, Australia.
28 92P The effects of acute exercise and creatine supplementation on Akt signalling in human skeletal muscle — R.J. Snow, C.R. Wright, M.J. Quick, A.P. Garnham, K.K. Watt and A.P. Russell, The Centre for Physical Activity and Nutrition Research (C-PAN), School of Exercise and Nutrition Sciences, Deakin University, VIC 3125, Australia.
29 93P Effects of exercise training and antioxidant supplementation on endothelial cell gene expression — A. Matsumoto,1 L.C. Ward,2 P.A. Wilce,2 S.A. Marsh,3 R.G. Fassett4 and J.S. Coombes,1 1School of Human Movement Studies, The University of Queensland, St Lucia QLD 4072, Australia, 2School of Molecular & Microbial Science, The University of Queensland, St Lucia QLD 4072, Australia, 3Department of Nutrition and Exercise Metabolism, Washington State University, PO Box 1495 Spokane WA 99210-1495, USA and 4Royal Brisbane Women's Hospital, GPO Box 48, Brisbane QLD 4001, Australia.
30 94P The effect of acute exercise on skeletal muscle SIRT1 — S.E. Heywood, G.D. Wadley and G.K. McConell, Exercise Physiology and Metabolism Laboratory, Department of Physiology, The University of Melbourne, VIC 3010, Australia.
31 95P Exercise-training increases skeletal muscle mitochondrial biogenesis despite inhibition of xanthine oxidase — M.A. Nicolas, G.K. McConell and G.D. Wadley, Department of Physiology, The University of Melbourne, Parkville, VIC 3010, Australia.
32 96P No effect of statins or ezetimibe on fat metabolism during aerobic exercise in dyslipidaemic individuals — M.A. Matuszek1 and R. Grant,1,2 1School of Medical Sciences, University of New South Wales, NSW 2052, Australia and 2Australasian Research Institute, Sydney Adventist Hospital, Wahroonga, NSW 2076, Australia.
33 97P Hyperaemic responses to forearm exercise — T. Van der Touw and M. Cook, School of Science and Technology, University of New England, Armidale, NSW 2351, Australia. (Introduced by Dr Gudrun Dieberg)
34 98P The response of isolated tunica dartos muscle to acute and prolonged cold stimulation and noradrenaline — I. Nanayakkara, S.K. Maloney and A.J. Bakker, Discipline of Physiology, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, WA 6009, Australia.
35 99P Uterine spontaneous contractions in the estrous cycle and the effect of mitochondrial inhibitors — F.S. Gravina,1 K.P. Kerr,1 S. Sandow,2 R.B. de Oliveira,1 H.C. Parkington,3 M.S. Imtiaz1 and D.F. van Helden,1 1School of Biomedical Sciences, University of Newcastle, NSW 2308, Australia, 2Department of Pharmacology, University of New South Wales, NSW 2052, Australia and 3Department of Physiology, Monash University, VIC 3800, Australia.
36 100P The pacemaker and pattern generator underlying colonic migrating motor complexes does not require release of serotonin from the mucosa — D.J. Keating and N.J. Spencer, Department of Human Physiology, School of Medicine, Flinders University, SA 5001, Australia.
37 101P Spatial relationships influence stimulus-secretion coupling in secretory epithelial cells — J. Low and P. Thorn, School of Biomedical Science, University of Queensland, QLD 4072, Australia.
38 102P EGF and neurotensin mediated proliferation in HT-29 colon cancer cells; defining a role for the scaffold protein NHERF-1 — W.A. Kruger,1 Y. Jang,1 G.R. Monteith2 and P. Poronnik,1 1School of Biomedical Science, University of Queensland, St Lucia, Qld 2072, Australia and 2School of Pharmacy, University of Queensland, St Lucia, Qld 4072, Australia.
39 103P Megalin binds to NHERF1 and NHERF2 scaffold proteins — K.A. Jenkin,1 C. Slattery,2 P. Poronnik2 and D.H. Hryciw,1 1School of Biomedical and Health Sciences, St Albans, Victoria University, VIC 8001, Australia and 2 School of Biomedical Sciences, The University of Queensland, St Lucia, QLD 4069, Australia.
40 104P Identification of glutamate transporter glast splice variants in hypoxic neonatal pig brain — A. Lee,1 S. O'Driscoll,2 D. Pow2 and P. Poronnik,1 1School of Biomedical Science, University of Queensland, Brisbane, Qld 4072, Australia and 2Centre for Clinical Research, University of Queensland, Royal Brisbane and Womens Hospital, Qld 4029, Australia.
41 105P Protons released as a by-product of exocytosis affect the intracellular calcium response — N. Behrendorff and P. Thorn, School of Biomedical Sciences, University of Queensland, St Lucia, QLD 4072, Australia.
42 106P Epithelial Sodium channels are regulated by the tyrosine kinase, c-Abl — S.H. Song, I.H. Lee, A. Dinudom and D.I. Cook, Discipline of Physiology, School of Medical Science, Faculty of Medicine, University of Sydney, Sydney, New South Wales 2006, Australia..
43 107P Regulation of the rat glutamine transporter SNAT3 — S. Balkrishna, A. Bröer, A. Kingsland and S. Bröer, School of Biochemistry and Molecular Biology, The Australian National University, Canberra, ACT 0200, Australia.
44 108P Distribution of the amino acid transporters B0AT1, B0AT2 and ASCT2 in kidney and intestine — N. Tietze,1 J.M. Vanslambrouck,2 J.E.J. Rasko2 and S. Bröer,1 1School of Biochemistry and Molecular Biology, The Australian National University, Canberra, ACT 0200, Australia and 2Gene and Stem Cell Therapy Program, Centenary Institute of Cancer Medicine and Cell Biology, University of Sydney, NSW 2050, Australia.
45 109P Human sarcopenia reveals an increase in SOCS-3 and myostatin and a reduced efficiency of Akt phosphorylation — B. Léger,1 W. Derave,2 K. De Bock,3 P. Hespel2 and A.P. Russell,4 1Institut de recherche en réadaptation-réinsertion, Avenue de Grandchampsec 90, Sion 1951, Switzerland, 2Research Centre for Exercise and Health, Faculty of Kinesiology and Rehabilitation Sciences, K.U.Leuven, B-3001, Belgium, 3Department of Movement and Sport Sciences, Ghent University, Ghent, Belgium and 4The Centre for Physical Activity and Nutrition Research (C-PAN), School of Exercise and Nutrition Sciences, Deakin University, VIC 3125, Australia.
46 110P Contribution of Nitric Oxide to vagal nerve function in the dystrophin deficient heart — M. Watson, E. Lee and A. Hoey, Centre for Systems Biology, University of Southern Queensland, QLD, Australia.
47 111P Phase resolved retardation measurements of isolated cardiomyocytes — N.M. Dragomir,1 C.L. Curl,2 A. Roberts1 and L.M.D. Delbridge,2 1School of Physics, University of Melbourne, Vic 3010, Australia and 2Department of Physiology, University of Melbourne, Vic 3010, Australia.
48 112P An optimized RNA extraction protocol for stored human myocardial tissue biopsies — W.T.K. Ip,1 C.E. Huggins,2 S. Pepe3 and L.M.D. Delbridge,1 1Cardiac Phenomics Laboratory, Department of Physiology, University of Melbourne, Parkville, VIC 3010, Australia, 2School of Exercise & Nutrition Sciences, Deakin University, Burwood, VIC 3125, Australia and 3Murdoch Children's Research Institute, Department of Cardiology, Royal Children's Hospital, Parkville, VIC 3010, Australia.
49 113P Concentration dependent modulation of the cardiac ryanodine receptor by Homer1 — P. Pouliquin, S.M. Pace and A.F. Dulhunty, Division of Molecular Bioscience, JCSMR, ANU, Canberra, ACT 2601, Australia.
50 114P F157A and Y160A substitutions in the helix 6 Region of GSTM2-2 C terminus reduces the inhibitory action of helix 6 on RyR2 channels — R. Hewawasam, D. Liu, M.G. Casarotto, P.G. Board and A.F. Dulhunty, Division of Molecular Bioscience, The John Curtin School of Medical Research, Australian National University, ACT 2601, Australia.
51 115P Biophysical investigations of the cyclised skeletal muscle dihydropyridine receptor II-III loop — H-S. Tae, P.G. Board, M.G. Casarotto and A. F. Dulhunty, Division of Molecular Bioscience, The John Curtin School of Medical Research, The Australian National University, ACT 2601, Australia.
52 116P Store independent activation and properties of Orai3/STIM1 mediated current — N.R. Scrimgeour and G.Y. Rychkov, Department of Physiology, University of Adelaide, Adelaide, 5005, Australia.
53 117P Selective and voltage dependent inhibition of N-type calcium channels by novel ω-Conotoxins CVIE and CVIF — G. Berecki,1,2 L. Motin,1,2 A. Haythornthwaite,2 N.L. Daly,3 P. Bansal,3 S. Vink,3 R. Drinkwater,4 R.J. Lewis,3,4 P.F. Alewood3 and D.J. Adams,1,2 1The Queensland Brain Institute, The University of Queensland, QLD 4072, Australia, 2The School of Biomedical Sciences, The University of Queensland, QLD 4072, Australia, 3The Institute for Molecular Biosciences, The University of Queensland, QLD 4072, Australia and 4Xenome Ltd, Indooroopilly, QLD 4069, Australia.
54 118P Influence of mitochondria in the interspike interval pacemaking currents of mice Locus Coeruleus neurons — R.B. de Oliveira, M. Howlett, F.S. Gravina, M.S. Imtiaz, R.J. Callister, A.M. Brichta and D.F. van Helden, School of Biomedical Sciences, University of Newcastle, NSW 2308, Australia.
55 119P Adiponectin causes insulin secretion with increased cytoplasmic calcium and inhibition of AMP Kinase in MIN6 cells — J.R. Rao,1,2 H.C. Parkington,2 D.J. Keating1 and C. Chen,1,2 1Prince Henry's Institute of Medical Research, Clayton, VIC 3168, Australia and 2Department of Physiology, Monash University, VIC 3800, Australia.
1530 Formal session ends

King Theatre

Chair: Stewart Head

Free communications: Muscle

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1545 120P Ageing alters the inflammatory response in rat skeletal muscles after injury — C. van der Poel,1 J.G. Ryall,1 J.D. Schertzer,1 L.E. Gosselin2 and G.S. Lynch,1 1Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, VIC 3010, Australia and 2Department of Exercise and Nutrition Sciences, University at Buffalo, Buffalo, NY 14214, USA.
1600 121P Influence of caveolin-3 upon membrane raft lipids and its implications for trafficking in muscle — O.L. Gervásio, W.D. Phillips and D.G. Allen, Bosch Institute, School of Medical Sciences, Anderson Stuart Building (F13), University of Sydney, NSW 2006, Australia.
1615 122P Myoplasmic and sarcoplasmic reticulum calcium in intact mouse muscle during fatigue — D.G. Allen,2 Y. Petersen,1 I. Röder1 and R. Rudolf,1 1Institute for Toxicology & Genetics, Forschungszentrum Karsruhe and KIT, 76021 Karlsruhe, Germany and 2School of Medical Sciences and Bosch Institute, University of Sydney, NSW 2006, Australia.
1630 123P Effect of S-nitrosoglutathione (GSNO) on excitation-contraction coupling in mechanically-skinned muscle fibres of the rat — T.L. Dutka, G.S. Posterino and G.D. Lamb, Department of Zoology, La Trobe University, Victoria 3086, Australia.
1645 Close

Wright Theatre

AuPS Invited Lecture &mdash Graham Lamb

Chair: David Adams

1700 124P Exciting muscles: ion channels and excitation-contraction coupling in exercise and disease — G.D. Lamb, Department of Zoology, La Trobe University, Bundoora, Melbourne, VIC 3086, Australia.
1830 for 1900 Conference Dinner - University House

Wednesday 3 December 2008

King Theatre

Symposium: Epithelial Cell Biology

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Chair: Stefan Bröer and Phil Poronnik

0830 125P Diabetes and ACE2; light on the dark side of the renin angiotensin system — M.C. Thomas, Baker IDI Heart and Diabetes Institute, PO Box 6492, St Kilda Rd Central, Melbourne, VIC 8008, Australia. (Introduced by Stefan Bröer)
0850 126P A GFP-based complementation screen for protein:protein interactions for the angiotensin type 1 receptor — W.G. Thomas, School of Biomedical Sciences, The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia.
0910 127P Extracellular pH shifts and their consequences for secretory epithelial cells — P. Thorn and N. Behrendorff, School of Biomedical Science, University of Queensland, QLD 4072, Australia.
0930 128P Purinergic regulation of epithelial Na+ channels — A. Dinudom, L.M. O'Mullane, C.R. Campbell and D.I. Cook, Discipline of Physiology and Bosch Institute, Faculty of Medicine, University of Sydney, NSW 2006, Australia.
0950 129P An insight into epithelial cells through rare disorders — S. Bröer, School of Biochemistry & Molecular Biology, College of Medicine, Biology and Environment, Australian National University, Canberra, ACT 0200, Australia.
1010 130P Insights into renal albumin handling — P. Poronnik, School of Biomedical Sciences, The University of Queensland, St Lucia, QLD 4072, Australia.
1030 Close

Wright Theatre

Symposium: Role of ROS in Cardiovascular Function and Disease

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Chair: Livia Hool and David Allen

0830 131P NADPH oxidase: role in muscular dystrophy — N.P. Whitehead and D.G. Allen, Discipline of Physiology, Bosch Institute, University of Sydney, NSW 2006, Australia.
0900 132P NADPH oxidases in vascular biology and disease — C.P. Judkins,1 H. Diep,1 B.R.S. Broughton,1 A.E. Mast,1 G.J. Dusting,2 C.G. Sobey1 and G.R. Drummond,1 1Department of Pharmacology, Monash University, Clayton, VIC 3800, Australia and 2Bernard O'Brien Institute of Microsurgery, Fitzroy, VIC 3065, Australia. (Introduced by David Allen)
0930 133P Crosstalk between the L-type Ca2+ channel and the mitochondria — L.C. Hool, H.M. Viola and P.G. Arthur, Cardiovascular Electrophysiology Laboratory, School of Biomedical Biomolecular and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia.
1000 134P Reactive oxygen species (ROS) and insulin resistant hypertrophic cardiomyopathy — L.M.D. Delbridge, Department of Physiology, University of Melbourne, VIC 3010, Australia.
1030 Close
1030-1100 Morning Tea - Alan Gilbert Building

King Theatre

Free communications: Membrane transport

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Chair: Dan Markovich

1100 135P A novel digestive complex and its role in Hartnup disorder: trafficking of the neutral amino acid transporter B0AT1 by angiotensin converting enzyme 2 (ACE2) — S. Kowalczuk,1 A. Bröer,1 N. Tietze,1 J.M. Vanslambrouck,2 J.E.J. Rasko2,3 and S. Bröer,1 1School of Biochemistry and Molecular Biology, Australian National University, Canberra, ACT 0200, Australia, 2Gene and Stem Cell Therapy Program, Centenary Institute of Cancer Medicine and Cell Biology, University of Sydney, Camperdown, NSW 2050, Australia and 3Cell and Molecular Therapies, Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia.
1115 136P Regulation of epithelial sodium channels by Gαq — I.H. Lee, A. Dinudom, S. Kumar and D.I. Cook, Discipline of Physiology, School of Medical Science, University of Sydney, NSW 2006, Australia.
1130 137P The epithelial sodium channel and blood pressure — C.J. Büsst, K.J. Scurrah, J.A. Ellis and S.B. Harrap, Department of Physiology, The University of Melbourne, VIC 3010, Australia.
1200 138P Huntingtin-Associated Protein 1 (HAP-1) is a novel regulator of exocytosis — D.J. Keating,1 L. Phillips,1 X.F. Zhou2 and K. Mackenzie,1 1Molecular and Cellular Neuroscience Group, Department of Human Physiology and Centre for Neuroscience, Flinders University, Adelaide, Australia, 5042 and 2Neuroregeneration Laboratory, Department of Human Physiology and Centre for Neuroscience, Flinders University, Adelaide, Australia, 5042.
1215 139P RCAN1 (Regulator of Calcineurin 1) is a novel regulator of secretory vesicle exocytosis and fusion pore kinetics — M.P. Zanin,1 M. Pritchard2 and D.J. Keating,1,3 1Molecular and Cellular Neuroscience Group, Department of Human Physiology and Center for Neuroscience, Flinders University, Adelaide, SA 5042, Australia, 2Centre for Functional Genomics and Human Disease, Monash Institute of Medical Research, Monash University, Clayton, VIC 3168, Australia and 3Prince Henry’s Institute of Medical Research, Clayton, VIC 3168, Australia.
1230 Close

Wright Theatre

Symposium: Cardiac Growth and Ageing

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Chair: Lea Delbridge and John Headrick

1100 140P Age-associated changes in cardiac excitation-contraction coupling in ventricular myocytes isolated from male and female Fischer 344 rats — S.E. Howlett, Dalhousie University, Department of Pharmacology, 5850 College Street, Halifax, Nova Scotia, Canada B3H 1X5. (Introduced by Lea Delbridge)
1130 141P Cardioprotective signalling in aging myocardium: failure of receptor-triggered protection — J.P. Headrick, J.N. Peart and K.J. Ashton, Heart Foundation Research Centre, Griffith University, Gold Coast, QLD 4217, Australia. (Introduced by Lea Delbridge)
1200 142P Phosphoinositide 3-kinase (PI3K, p110α) and adaptive growth in the heart — J.R. McMullen, Cardiac Hypertrophy, Baker IDI Heart & Diabetes Institute, Melbourne, VIC 8008, Australia. (Introduced by L. M. Delbridge)
1230 143P Metabolic challenges for cardiac mitochondria: from womb to tomb — S. Pepe, Murdoch Children’s Research Institute, Department of Cardiology, Royal Children's Hospital, Flemington Rd., Melbourne, VIC 3052, Australia. (Introduced by Lea M.D. Delbridge)
1300 Close

Gilbert Building

AuPS AGM (& lunch)

1300 Start

Wright Theatre

The Physiological Society (UK) Exchange Lecture - Colin Sibley

Chair: Joe Lynch

1430 144P Fetal growth and placental physiology: From cell to community — C.P. Sibley, Maternal and Fetal Health Research Group, University of Manchester, St. Mary's Hospital, Manchester, M13 0JH, UK.
1530 Close

Wright Theatre

Prizes

1530 Presentations
1600 Close
1600 End of conference