Australian Physiological Society
The professional association for Australian Physiologists
The professional association for Australian Physiologists
| VOLUME 52 - Hobart 2022 | |||
| Seeing the baby grow: MRI to measure placental and cardiac function in the fetus | Prof Janna Morrison | 1I | |
| Acetylation of myofilament proteins modulate diastolic function | Kathleen Woulfe University of Colorado | 2S | |
| Cardiac protein phosphatases: more than an 'off' switch for protein kinases | Kate Weeks University of Melbourne | 3S | |
| Adiponectin signalling as a therapeutic target for diabetic cardiomyopathy and heart failure | Miles De Blasio Monash University | 4S | |
| Physiological Society NZ, New & Emerging Researcher Award - 2022 Winner: Reinstating heart rate variability restores cardiac function in chronic heart failure sheep | Julia Shanks University of Auckland | 5S | |
| The role of pericytes in the regulation of brain blood flow and their dysfunction in dementia | Brad Sutherland, University of Tasmania | 6S | |
| Transcriptomic profiling of the mouse aorta to identify novel cellular drivers of aortic stiffening in hypertension | Maria Jelinic, La Trobe University | 7S | |
| Harnessing non-invasive ultrasound to understand brain blood flow regulation following stroke | Dino Premilovac University of Tasmania | 8S | |
| Muscle microvascular flow regulation in health and disease | Michelle Keske Deakin University | 9S | |
| The gut/liver axis: a novel therapeutic approach to treat NASH | Michael Karin UCSD | 10S | |
| Using single Nucleus RNA sequencing of pre-malignant liver to predict NASH driven liver cancer | Nina Tirnitz-Parker Curtin University | 11S | |
| Identification of a blood biomarker to predict NASH driven liver cancer | Benoit Smeuninx Monash University | 12S | |
| Mouse strain-dependent variation in the NASH lipidome - Novel therapeutic avenues for NAFLD | Magda Montgomery University of Melbourne | 13S | |
| Interrogating the biological roles of dystrophin and utrophin in dystrophic muscle adaptations to exercise | Justin Hardee | 15O | |
| The effect of gestational stress on behavioral and physiological phenotypes in the dystrophin-deficient mdx mouse | Saba gharibi | 16O | |
| Muscle stem cell function is maintained in mouse models of type 1 diabetes | Jin Chung | 17O | |
| Fibre type-specific abundance of dysferlin in rodent skeletal muscle | Stefan Wette | 18O | |
| Isolated Extensor Digitorum Longus muscles from old mdx dystrophic mice show little force recovery 120 minutes after eccentric damage | Leonit Kiriaev | 19O | |
| Phosphorylation of C18ORF25 regulates skeletal muscle function | Ronnie Blazev | 20O | |
| Biomechanical properties of dysferlin-deficient skeletal muscle and the impact of muscle type and age | Erin Lloyd | 21O | |
| MicroRNA-205: a novel epicardial regulator of cell cycle and cardiac growth in the perinatal heart | Patrick Burgon | 22O | |
| Bitter Taste Receptors (T2Rs) in the Heart - a New Cardiovascular Physiology? | Walter Thomas | 23O | |
| Inactivation of the local cardiac renin angiotensin system improves cardiac performance after myocardial infarction | Zunha Lu | 24O | |
| AAV-directed expression of Neuregulin 1-b1 drives cardiac enlargement in neonatal mice - a critical role for Neuregulin 1-b1 and ErbB4 in postnatal cardiomyocyte survival | Hui Yi Khoo | 25O | |
| MiR-558 inhibitor induces cardiac proliferation after myocardial infarction | Catherine Dimasi | 26O | |
| Post-weaning early life dietary macronutrient balance variably affects biometric and metabolic outcomes in adulthood | Adam Rose | 27O | |
| The designer cytokine IC7Fc promotes weight loss by decreasing digestive efficiency in obese mice | Gideon Kang | 28O | |
| Pericyte characterisation in healthy and type 2 diabetic skeletal muscle microvasculature | Emily Attrill | 29O | |
| Ceramide metabolism in skeletal muscle - questioning previous models | Sarah Turpin-Nolan | 30O | |
| Loss of Acyl-CoA dehydrogenase family member (ACAD10) does not alter whole-body metabolism or metformin action | Darren Henstridge | 31O | |
| Control of metabolism by proglucagon-derived hormones from the gut | Damien Keating Flinders University | 32S | |
| The role of a bile acid-GLP1 axis in the regulation of glucose metabolism | Tongzhi Wu The University of Adelaide | 33S | |
| Integration of glucose and amino acid metabolism by glucagon | Clinton Bruce Deakin University | 34S | |
| Hepatic glucagon action in obesity and type 2 diabetes: insights from mouse models | Yuqin WU Monash University | 35S | |
| Why retractions are growing so fast - and why there still aren't enough | Ivan Oransky Retraction Watch | 36S | |
| Research Quality: you should be worried! | Simon Gandevia NeuRA | 37S | |
| Freezer Study: An Investigation of the Stability of Skeletal Muscle Proteins after prolong freezer storage | Noni Frankenberg La Trobe University | 38S | |
| Technical considerations when assessing gene expression in human skeletal muscle using quantitative real-time PCR | Jujiao Kuang Victoria University | 39S | |
| 2020 Prize Winner: Empowering student ownership through flexibility, authenticity, and co-creation | Dr Charles Sevigny University of Melbourne | 40I | |
| 2021 Prize Winner: The school of hard knocks: what did not work when introducing technology-enhanced learning to physiology lectures, labs and workshops. | A/Prof Christian Moro Bond University | 41I | |
| Characterising brain inflammation during pregnancy in a new mouse model of metabolic syndrome | Abdiweli Warsame | 42O | |
| Thyroglobulin antibody positivity induces maternal hyperglycaemia and increases placental weight in a Lewis rat model | Nykola Kent | 43O | |
| The Effects of Maternal Hyperglycaemia During Pregnancy on One-Carbon Metabolism | Dayna Zimmerman | 44O | |
| Metabolic syndrome in pregnancy causes fetal growth restriction and attenuates placental leukocyte populations | Maral Baghaei | 45O | |
| Transthyretin binds to soluble endoglin: a possible role for transthyretin in the prevention of preeclampsia? | Melanie Young | 46O | |
| The abundance of cell-free mitochondria are increased in human blood following an acute bout of endurance exercise | Glenn Wadley | 47O | |
| Preliminary results from an investigation of exercise timing to mitigate postprandial hyperglycaemia and vascular dysfunction in healthy adults | Laura Smith | 48O | |
| C18ORF25 is a novel exercise-regulated AMPK substrate regulating skeletal muscle function | Kit Ng | 49O | |
| Metabolomic analysis of mouse skeletal muscle and liver responses to acute exercise and disruption of AMPK-glycogen binding | Mehdi Belhaj | 50O | |
| The role of testosterone in skeletal muscle adaptation to resistance training in pre-menopausal females | Sarah Alexander | 51O | |
| Obesity and the brain- how disrupting neural networks causes diabetes | Garron Dodd | 53S | |
| Obesity and cancer- metabolic reprogramming and cancer progression | Renea Taylor Monash University | 54S | |
| Obesity and reproduction- oocyte quality and fertility | Rebecca Robker University of Adelaide | 55S | |
| TBC | | 56S | |
| Novel primary afferent auditory and vestibular neuron phenotypes in the mouse inner ear resolved using peripherin promoter-driven transgene reporters and subtype-selective immunofluorescence | Lily Pearson | 57O | |
| Maintenance of hearing sensitivity in an ultraquiet environment requires olivocochlear efferent feedback | Jennie Cederholm | 58O | |
| Impaired neuromuscular signalling is a feature of Motor Neuron Disease | Peter Noakes | 59O | |
| Single point mutation of miRNA-873 and the synaptic protein neurexin induce autism-like behavioural changes and hippocampal dysfunction in a mouse model. | Helena Parkington | 60O | |
| Epileptic Encephalopathies associated with gain-of-function GABAA receptor variants are more severe than loss | Nathan Absalom | 61O | |
| Microglia Associate with the Vasculature and Pericytes in the Healthy and Inflamed Brain | Catherine Foster | 62O | |
| Ablation of pericytes impedes motor function, induces blood-brain barrier leakage, and stimulates glial cell activation | Jake Cashion | 63O | |
| Insulin infusion increases brain blood flow in healthy Sprague Dawley rats | Nicole Sumargo | 64O | |
| Characterisation of placental-specific cytochrome P450 enzyme activity in response to fetal growth restriction | Ashley Meakin University of South Australia | 65S | |
| Placental one carbon metabolism and complications of pregnancy | James Cuffe University of Queensland | 66S | |
| Oxidative stress and the placental renin-angiotensin system | Sarah Delforce University of Newcastle | 67S | |
| The Placenta: A Window into Maternal Disease | Rebecca Simmons University of Pennsylvania | 68S | |
| Transciptome analysis of the effects of polarized photobiomodulation on human dermal fibroblasts | Nicholas Tripodi | 69O | |
| Identification and characterization of a novel SNAT2 (SLC38A2) inhibitor reveals synergy with glucose transport inhibition in cancer cells | Stefan Broer | 70O | |
| Sulforaphane attenuates cancer-induced muscle wasting in C2C12 myotubes | Wenlan Li | 71O | |
| A combination screen finds inhibition of GCN2 sensitises growth of MDA-MB-231 and HPAFII cancer cell lines to CDK inhibitors | Gregory Gauthier-Coles | 72O | |
| Treatment of non-alcoholic steatohepatitis with the designer cytokine IC7Fc | Jingjing Zhao | 73O | |
| Urinary bladder contractions and the influence of extracellular calcium | Charlotte Phelps | 74O | |
| Novel role for protein kinase D in cardiac extracellular matrix signalling | Mark Renton | 75O | |
| Liver-derived small extracellular vesicles regulate glycemic control through increased insulin secretion and enhanced glucose effectiveness | Paula Miotto | 76O | |
| Strange species-specific sugar metabolic adaptations yield cardiac pathophysiology insights | Dunja Aksentijevic Queen Mary University of London | 77S | |
| The atypical Alpha Kinase 3 regulates sarcomeric protein metabolism in cardiomyopathy | James McNamara Murdoch Children's Research Institute | 78S | |
| Lipid dysregulation and cardio - vascular implications | Anna Calkin Baker Heart & Diabetes Institute | 79S | |
| Reinstating heart rate variability improves cardiac output in heart failure - novel metabolic insights from proteomics | David Crossman University of Auckland | 80S | |
| Optogenetic approaches for the modulation of membrane excitability and synaptic plasticity | John Lin University of Tasmania | 81S | |
| Neuromodulation of striatal neurons and the encoding of goal-directed learning | Chelsea Goulton UNSW Sydney | 82S | |
| Remapping neural circuits to mediate cross modal plasticity between seeing and feeling | Hiroaki Wake Nagoya, Japan | 83S | |
| Neural circuits that mediate drinking | Bowen Dempsey Macquarie University | 84S | |
| Mechanotransduction in Neutrophils | Sara Baratchi | 85O | |
| Structural mechanisms of human Aquaporin-1 ion channel gating and block by divalent cations, analysed by histidine scanning mutagenesis. | Andrea Yool | 86O | |
| Development of a multiplexed biophysical method of analysis for quantification of DNA repair factor dynamics. | Shikun (Tony) Ma | 87O | |
| A novel triglyceride tethered bilayer lipid membrane (tBLM) architecture | Upeksha Shashikala (Randunu) Mirissa Lankage | 88O | |
| Hyper-phosphorylation induces structural alterations and exacerbates the cytotoxicity of alpha-synuclein in Parkinson's Disease pathogenicity | Minal Chaturvedi | 89O | |
| A molecular mechanism for the lupus causing mutation in the RNA receptor TLR7 | Ben Corry | 90O | |
| Using Tethered Bilayer Lipid Membranes to test Phospholipase A2 Activity as a Biomarker for IBD Flare Events | Harry Clarke | 91O | |
| Nanotechnology and biopharmaceutics: molecular engineering of self-assembling therapeutic peptides for intrinsic nano-formulation | Celine Valery | 92O | |
| The synergy of a Lactoferrin-derived peptide with the antifungal drug Amphotericin B is lipid-mediated | Lissy Maike Hartmann | 93O | |
| Perfringolysin O pore formation dynamics: monomeric interactions, membrane tracking and membrane composition effects | Conall Mc Guinness | 94O | |
| Spatiotemporally Mapping Thermal Dynamics of Lysosomes and Mitochondria using Cascade Organelle-Targeting Upconversion Nanoparticles | Qian (Peter) Su | 95O | |
| A fluorescently-tagged peptide toxin, Cy5-HsTX1[R14A], as a tool for KV1.3 visualisation | Dorothy Wai | 96O | |
| 3D super-resolution imaging of whole nuclear lamina | Ashley Rozario | 97O | |
| Investigating biological noise: building a tuneable model system with DNA nanotechnology and droplet hydrogel bilayers | Alexander Mason | 98O | |
| From Superbugs to tBLMs: increasing the complexity in model membrane systems. | Ingo Koeper | 99O | |
| Effect of membrane composition on lipid packing and solute permeability. | Lauren Lowe | 100O | |
| Rational design of potent ultrashort antimicrobial peptides with programmable assembly into nanostructured hydrogels | Priscila Cardoso | 101O | |
| Single-molecule genotyping of thousands of variants | Lisanne Spenkelink | 102O | |
| Deep eutectic solvents for cryopreservation | Saffron Bryant | 103O | |
| Brightness cross correlation spectroscopy quantifies protein dynamics as a function of stoichiometry within live cells. | Ashleigh Solano | 104O | |
| Ultra-resolution in the cell nucleus with single molecule expansion microscopy | Toby Bell | 105O | |
| Behavior of citrate-capped ultrasmall gold nanoparticles on a supported lipid bilayer interface at atomic resolution | Rashad Kariuki | 106O | |
| Tracking the nuclear wide dynamics of live cell nucleosome proximity by fluorescence | Elizabeth Hinde | 107O | |
| How Do Steroids Impact Batten's Disease? | Trang Do Le | 108O | |
| Interrogating the biophysics of protein cage nanoreactors | Yu Heng Lau | 109O | |
| Behaviour of citrate-capped gold nanoparticles at biomembranes - atomic insight at supported lipid bilayer and liposome interfaces. | Aaron Elbourne | 110O | |
| A multi-scale kinetic and spatial model of yeast replication and prion transmission | Damien Hall | 111O | |
| How an acid trip saves malaria: a proton-transfer mechanism for the malaria lactate-proton transporter PfFNT | Ciara Wallis | 112O | |
| Computational modelling of metabolism within the ageing heart | Michael Pan | 113O | |
| Utilising Enhanced Sampling to Resolve a Conducting Conformation of the CFTR Ion Channel | Miro Astore | 114O | |
| Australia wide concensus on Core Concepts in Physiology | Kathy Tangalakis | 115E | |
| Re-creating an introductory physiology unit in the Core Concepts form | Sarah Etherington | 116E | |
| Incorporating planetary health concepts into physiology. | Christian Moro | 117E | |
| Clinical and Translational Physiology: Student perception of processed based learning to create an Authentic learning experience | Yossi Rathner | 118E | |
| Alumni graduate career pathways as a learning tool to assist career planning | Caroline Taylor | 119E | |
| A journey to BSEEN: bringing career pathways to the Biomedical Science experience | Judit Kibedi | 120E | |
| Redesigning a subject: What do students think of pre-recorded videos and high-stake team projects? | Angelina Fong | 121E | |
| The use of online resources to explain difficult physiological concepts by medical students at a Middle Eastern university - shouldn't we do something about this? | Sean Holroyd | 122E | |
| Curating student learning in virtual galleries | Craig Campbell | 123E | |
| Predicting Physiology Student Performance from LMS Data in the Post-COVID Era | Ari Pinar | 124E | |
| To Quitch or not to Quitch: Using a gamified mobile app to increase student performance and engagment | Iris Lim | 125E | |
| Can an anatomy and physiology bridging program impact first year University science engagement? | Puspha Sinnayah | 126E | |
| The pleasures and perils of virtual undergraduate biomedical industry placements | Julia Choate Monash University | 127E | |
| Building career awareness and skills throughout the Health Sciences Degree | Brianna Julien and Louise Lexis La Trobe University | 128E | |
| Enriching a WIL experience by fostering habits of head, heart and hand | Dr Chris Adams University of Tasmania | 129E | |
| Employability for Science Degrees: foundations, challenges and options | Liz Johnson Deakin University | 130E | |
| How equipped are first year undergraduate students in navigating common teamwork challenges? | Nilushi Karunaratne | 131E | |
| Evaluating students' awareness of their group work capabilities in physiology laboratory classes | Kay Colthorpe | 132E | |
| Students designing for students - using a "deteriorating patient" to teach second year physiology | Melissa Cameron | 133E | |
| Comparing student and academic grading of assessment tasks in an introductory neuroscience course | Jennie Cederholm | 134E | |
| Too many is not enough: exploring effective motivation strategies in nursing and midwifery students | Luli Faber | 135E | |
| Introducing learning workshops into the biosciences: A student-staff partnership | Louise Ainscough | 136E | |
| Developing C-reactive protein modulators as new treatments for inflammation | Karen S Cheung | 137O | |
| A multiscale model of calcium release reveals a novel mechanism for calcium wave initiation | Derek Laver | 138P | |
| The relationship between muscle mass and function with bone remodelling markers in older adults: effects of acute aerobic and resistance exercise | Cassandra Smith | 139P | |
| LncRNA Tug1 regulates expression of the mitochondrial calcium uniporter complex in myotubes and cardiomyocytes. | Adam Trewin | 140P | |
| Subtype-specific block of glioblastoma motility through dual inhibition of water and ion flux | Alanah Varricchio | 141P | |
| Learning from skeletal muscle to treat metastatic cancer | Alastair Saunders | 142P | |
| New insights into assessment of mitochondrial dysfunction and oxidative stress in preclinical models of diabetic cardiomyopathy | Alex Parker | 143P | |
| Differential responses in muscle atrogene expression in a mouse model of critical illness | Amy Bongetti | 144P | |
| Effects of sex on skeletal muscle phenotype in heart failure patients | Annabel Critchlow | 145P | |
| The role of N-acetylcysteine (NAC) in reducing pathological skeletal muscle fibre branching in an mdx mouse model of human Duchenne Muscular Dystrophy | Asma Redwan | 146P | |
| Is near-infrared spectroscopy a valid method for measuring skeletal muscle microvascular blood flow? Emily Wordie-Thompson | 147P | ||
| Response of circulating miRNAs to acute exercise: A systematic Review and Meta-Analysis | Danielle Hiam | 148P | |
| Establishing a platform mediated avoidance paradigm in female rats | Elise Cleary | 149P | |
| The cardiovascular effects of mechanical ventilation | Ella Smalley | 150P | |
| Establishing a platform mediated avoidance paradigm in male rats | Fergus Scott | 151P | |
| Sex differences in cardiovascular risk factor responses to resistance and endurance training in a primary prevention cohort | Hannah Thomas | 152P | |
| What to do when Westerns go wild | Heidy Latchman | 153P | |
| Can an old dog learn new tricks? Novel applications of Microdialysis for detecting skeletal muscle reactive oxygen species and assessing microvascular endothelial function in hypertensive populations | Hollie Speer | 154P | |
| Integrative transcriptomic and proteomic analysis show circulating osteoprogenitors to have a mixed immune and mesenchymal progenitor function in humans | Jack Feehan | 155P | |
| Calcium release-activated channel activity in the uterus - CRAC-ing labour contractions | Jawaher Alfaidi | 156P | |
| A single session of high intensity interval exercise in hypoxia modulates changes in mitochondrial biogenesis related gene and protein in human skeletal muscle | Jia Li | 157P | |
| Metabolic regulation of skeletal muscle regeneration after injury | John Nguyen | 158P | |
| High-glucose ingestion and acute exercise elicit dynamic and individualised responses in systemic markers of redox homeostasis. | Lewan Parker | 159P | |
| Characterising the opposing impact of obesity and exercise training on the cardiac phenotype in mice | Nimna Perera | 160P | |
| Thyroglobulin antibodies impair fertility and litter parameters and impact fetal survival in a rodent model of Autoimmune Thyroiditis | Rebecca Brady | 161P | |
| Hematopoietic Prostaglandin D Synthase Inhibitor PK007 Decreases Muscle Necrosis in DMD mdx Model Mice | Sai Yarlagadda | 162P | |
| Regeneration of mouse skeletal muscle after myotoxic injury is impacted by fucoidan supplementation | Samantha Kucewicz | 163P | |
| Utilizing a "four core genotypes" rat model to investigate sex differences in human disease | Shanie Landen | 164P | |
| Regular insulin administration increases muscle mass and exercise performance in otherwise healthy Sprague Dawley rats | Sophie Mayne | 165P | |
| Vascular RAGE and AGE binding protein expression and function in gestational diabetes. | Timothy Murphy | 166P | |
| Autophagy Flux in Human Peripheral Blood Mononuclear Cells in the 24 h Fasted and Fed State | Vicky Kuriel | 167P | |
| The urothelium and lamina propria as an alternative target for clinical antimuscarinics | Vineesha Veer | 168P | |
| What makes a good B0AT1 (SLC6A19) inhibitor? | Yashan Jiang | 169P | |
| Machine learning approaches for the discovery and optimization of oxazolidinones with therapeutic potential | McKenna Buckley | 170P | |
| The mechanism and structural basis of ion conduction in an inward rectifier potassium channel | Ruitao Jin | 171P | |
| Investigating molecular dynamics and sequence dependency of invading DNA strand in Homologous recombination double strand break repair | Cheree Fitzgibbon | 172P | |
| Cardiac forces regulate zebrafish heart valve delamination by modulating Nfat signaling | Wei-Yan Chow | 173P | |
| Elucidating mitochondrial dynamics and localisation upon T cell activation through advanced microscopy | Sofia Alfonso | 174P | |
| Benchmarking biophysical readouts of nanoscale chromatin compaction in live cells. | Kedi Wang | 175P | |
| Super-Resolution Analysis of Bisphenol A Effects on Meiotic Recombination in spermatocytes | Lynette Mirembe | 176P | |
| Application of super resolution microscopy to visualise immune activated interactions between lipid droplets and STAT proteins | Abbey Milligan | 177P | |
| Imaging changes to the membranes of live fungal cells caused by exposure to gold nanoparticles | Rowan Penman | 178P | |
| Identifying Lipid Mixtures for Optimal Tethered Bilayer Lipid Membrane Sensing of Lipase Activity | Samara Bridge | 179P | |
| Structure-function insight into the two-component DNA repair system of Mycobacterium tuberculosis | Joydeep Baral | 180P | |
| IP3R activity increases propensity of RyR-mediated Ca2+ sparks by elevating dyadic [Ca2+] | Joshua Chung | 181P | |
| Simulating the effects of delipidation on the mechanosensitive channel of small conductance MscS | Yiechang Lin | 182P | |
| Image correlation spectroscopy of DNA double strand break repair foci structure | Niall Karunaratne | 183P | |
| Structure-activity relationship of a-conotoxin Mr1.1 at the human a9a10 nicotinic acetylcholine receptor | Han-Shen Tae | 184P | |
| Involvement of Alpha-Subunit N-Termini in the Mechanism and Regulation of the Na+,K+-ATPase | Milna Chennath | 185P | |
| A hybrid approach to membrane disruption based intracellular delivery | William Hansen | 186P | |
| Single-molecule genotyping of thousands of variants | Stefan Mueller | 187P | |
| Disparate sodium channel inhibitors bind promiscuously inside the pore | Elaine Tao | 188P | |
| How the world lost one of its most effective anti-malarials to mutations in a Malarial multi-drug resistance protein: a molecular perspective | John Tanner | 189P | |
| Controllable liposome binding interactions using PEG-mediated DNA nanostructures | James Gaston | 190P | |
| Susceptibility of leukemia cells to synergistic treatment with vitamin C and select flavonoids | Suganeya Soundararajana | 191P | |
| Isoform specificity of Na+, K+-ATPase regulation by protein kinase C | Emma-Lucille Blayney | 192P | |